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Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior.
Brachman RA, McGowan JC, Perusini JN, Lim SC, Pham TH, Faye C, Gardier AM, Mendez-David I, David DJ, Hen R, Denny CA. Brachman RA, et al. Among authors: david dj. Biol Psychiatry. 2016 May 1;79(9):776-786. doi: 10.1016/j.biopsych.2015.04.022. Epub 2015 May 4. Biol Psychiatry. 2016. PMID: 26037911 Free PMC article.
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus.
Saxe MD, Battaglia F, Wang JW, Malleret G, David DJ, Monckton JE, Garcia AD, Sofroniew MV, Kandel ER, Santarelli L, Hen R, Drew MR. Saxe MD, et al. Among authors: david dj. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17501-6. doi: 10.1073/pnas.0607207103. Epub 2006 Nov 6. Proc Natl Acad Sci U S A. 2006. PMID: 17088541 Free PMC article.
Efficacy of the MCHR1 antagonist N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in mouse models of anxiety and depression following acute and chronic administration is independent of hippocampal neurogenesis.
David DJ, Klemenhagen KC, Holick KA, Saxe MD, Mendez I, Santarelli L, Craig DA, Zhong H, Swanson CJ, Hegde LG, Ping XI, Dong D, Marzabadi MR, Gerald CP, Hen R. David DJ, et al. J Pharmacol Exp Ther. 2007 Apr;321(1):237-48. doi: 10.1124/jpet.106.109678. Epub 2007 Jan 19. J Pharmacol Exp Ther. 2007. PMID: 17237257
302 results