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Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12.
Garris CS, Arlauckas SP, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, Pierce RH, Le MH, Algazi AP, Daud AI, Pai SI, Zippelius A, Weissleder R, Pittet MJ. Garris CS, et al. Among authors: daud ai. Immunity. 2022 Sep 13;55(9):1749. doi: 10.1016/j.immuni.2022.07.021. Immunity. 2022. PMID: 36103861 No abstract available.
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12.
Garris CS, Arlauckas SP, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, Pierce RH, Le MH, Algazi AP, Daud AI, Pai SI, Zippelius A, Weissleder R, Pittet MJ. Garris CS, et al. Among authors: daud ai. Immunity. 2018 Dec 18;49(6):1148-1161.e7. doi: 10.1016/j.immuni.2018.09.024. Epub 2018 Dec 11. Immunity. 2018. PMID: 30552023 Free PMC article.
Prognostic Biomarkers for Melanoma Immunotherapy.
Twitty CG, Huppert LA, Daud AI. Twitty CG, et al. Among authors: daud ai. Curr Oncol Rep. 2020 Feb 11;22(3):25. doi: 10.1007/s11912-020-0886-z. Curr Oncol Rep. 2020. PMID: 32048065 Review.
Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma.
Algazi AP, Twitty CG, Tsai KK, Le M, Pierce R, Browning E, Hermiz R, Canton DA, Bannavong D, Oglesby A, Francisco M, Fong L, Pittet MJ, Arlauckas SP, Garris C, Levine LP, Bifulco C, Ballesteros-Merino C, Bhatia S, Gargosky S, Andtbacka RHI, Fox BA, Rosenblum MD, Daud AI. Algazi AP, et al. Among authors: daud ai. Clin Cancer Res. 2020 Jun 15;26(12):2827-2837. doi: 10.1158/1078-0432.CCR-19-2217. Epub 2020 May 6. Clin Cancer Res. 2020. PMID: 32376655 Free PMC article. Clinical Trial.
Intratumoral Plasmid IL12 Electroporation Therapy in Patients with Advanced Melanoma Induces Systemic and Intratumoral T-cell Responses.
Greaney SK, Algazi AP, Tsai KK, Takamura KT, Chen L, Twitty CG, Zhang L, Paciorek A, Pierce RH, Le MH, Daud AI, Fong L. Greaney SK, et al. Among authors: daud ai. Cancer Immunol Res. 2020 Feb;8(2):246-254. doi: 10.1158/2326-6066.CIR-19-0359. Epub 2019 Dec 18. Cancer Immunol Res. 2020. PMID: 31852717 Free PMC article. Clinical Trial.
The Liver-Immunity Nexus and Cancer Immunotherapy.
Lee JC, Green MD, Huppert LA, Chow C, Pierce RH, Daud AI. Lee JC, et al. Among authors: daud ai. Clin Cancer Res. 2022 Jan 1;28(1):5-12. doi: 10.1158/1078-0432.CCR-21-1193. Epub 2021 Jul 20. Clin Cancer Res. 2022. PMID: 34285059 Free PMC article. Review.
Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of plasmid CXCL9 synergizes with plasmid IL-12 therapy to elicit robust anti-tumor immunity.
Lee JY, Nguyen B, Mukhopadhyay A, Han M, Zhang J, Gujar R, Salazar J, Hermiz R, Svenson L, Browning E, Lyerly HK, Canton DA, Fisher D, Daud A, Algazi A, Skitzki J, Twitty CG. Lee JY, et al. Mol Ther Oncolytics. 2022 Apr 18;25:174-188. doi: 10.1016/j.omto.2022.04.005. eCollection 2022 Jun 16. Mol Ther Oncolytics. 2022. PMID: 35592387 Free PMC article.
199 results