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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Deprez-Poulain R, Hennuyer N, Bosc D, Liang WG, Enée E, Marechal X, Charton J, Totobenazara J, Berte G, Jahklal J, Verdelet T, Dumont J, Dassonneville S, Woitrain E, Gauriot M, Paquet C, Duplan I, Hermant P, Cantrelle FX, Sevin E, Culot M, Landry V, Herledan A, Piveteau C, Lippens G, Leroux F, Tang WJ, van Endert P, Staels B, Deprez B. Deprez-Poulain R, et al. Among authors: dassonneville s. Nat Commun. 2015 Sep 23;6:8250. doi: 10.1038/ncomms9250. Nat Commun. 2015. PMID: 26394692 Free PMC article.
Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737.
Mathieu AL, Sperandio O, Pottiez V, Balzarin S, Herlédan A, Elkaïm JO, Fogeron ML, Piveteau C, Dassonneville S, Deprez B, Villoutreix BO, Bonnefoy N, Leroux F. Mathieu AL, et al. Among authors: dassonneville s. J Biomol Screen. 2014 Aug;19(7):1035-46. doi: 10.1177/1087057114534070. Epub 2014 May 8. J Biomol Screen. 2014. PMID: 24809353
Potential for Drug-Drug Interactions between Antiretrovirals and HCV Direct Acting Antivirals in a Large Cohort of HIV/HCV Coinfected Patients.
Poizot-Martin I, Naqvi A, Obry-Roguet V, Valantin MA, Cuzin L, Billaud E, Cheret A, Rey D, Jacomet C, Duvivier C, Pugliese P, Pradat P, Cotte L; Hepadat'AIDS Study Group. Poizot-Martin I, et al. PLoS One. 2015 Oct 21;10(10):e0141164. doi: 10.1371/journal.pone.0141164. eCollection 2015. PLoS One. 2015. PMID: 26488159 Free PMC article.