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Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure-activity relationship and unique pyrrolylation of primary amines.
Dasari R, Masi M, Lisy R, Ferdérin M, English LR, Cimmino A, Mathieu V, Brenner AJ, Kuhn JG, Whitten ST, Evidente A, Kiss R, Kornienko A. Dasari R, et al. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4544-8. doi: 10.1016/j.bmcl.2015.08.066. Epub 2015 Aug 24. Bioorg Med Chem Lett. 2015. PMID: 26341136 Free PMC article.
Chemistry and biology of ophiobolin A and its congeners.
Masi M, Dasari R, Evidente A, Mathieu V, Kornienko A. Masi M, et al. Among authors: dasari r. Bioorg Med Chem Lett. 2019 Apr 1;29(7):859-869. doi: 10.1016/j.bmcl.2019.02.007. Epub 2019 Feb 7. Bioorg Med Chem Lett. 2019. PMID: 30765189 Review.
Sesterterpenoids with Anticancer Activity.
Evidente A, Kornienko A, Lefranc F, Cimmino A, Dasari R, Evidente M, Mathieu V, Kiss R. Evidente A, et al. Among authors: dasari r. Curr Med Chem. 2015;22(30):3502-22. doi: 10.2174/0929867322666150821101047. Curr Med Chem. 2015. PMID: 26295461 Free PMC article. Review.
Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines.
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Kälin RE, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A. Dasari R, et al. Eur J Med Chem. 2015 Oct 20;103:226-37. doi: 10.1016/j.ejmech.2015.08.047. Epub 2015 Aug 29. Eur J Med Chem. 2015. PMID: 26360047 Free PMC article.
Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug-Resistant Cancer Cells.
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A. Dasari R, et al. ChemMedChem. 2015 Dec;10(12):2014-26. doi: 10.1002/cmdc.201500360. Epub 2015 Oct 5. ChemMedChem. 2015. PMID: 26434977 Free PMC article.
5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells.
Henry S, Kidner R, Reisenauer MR, Magedov IV, Kiss R, Mathieu V, Lefranc F, Dasari R, Evidente A, Yu X, Ma X, Pertsemlidis A, Cencic R, Pelletier J, Cavazos DA, Brenner AJ, Aksenov AV, Rogelj S, Kornienko A, Frolova LV. Henry S, et al. Among authors: dasari r. Eur J Med Chem. 2016 Sep 14;120:313-28. doi: 10.1016/j.ejmech.2016.05.004. Epub 2016 May 6. Eur J Med Chem. 2016. PMID: 27218860 Free PMC article.
262 results