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TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure.
Lorenzana-Carrillo MA, Gopal K, Byrne NJ, Tejay S, Saleme B, Das SK, Zhang Y, Haromy A, Eaton F, Mendiola Pla M, Bowles DE, Dyck JRB, Ussher JR, Michelakis ED, Sutendra G. Lorenzana-Carrillo MA, et al. Among authors: das sk. Sci Transl Med. 2022 Nov 2;14(669):eabm3565. doi: 10.1126/scitranslmed.abm3565. Epub 2022 Nov 2. Sci Transl Med. 2022. PMID: 36322626
p53-Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio-oncology.
Saleme B, Das SK, Zhang Y, Boukouris AE, Lorenzana Carrillo MA, Jovel J, Wagg CS, Lopaschuk GD, Michelakis ED, Sutendra G. Saleme B, et al. Among authors: das sk. J Am Heart Assoc. 2020 Aug 4;9(15):e017247. doi: 10.1161/JAHA.120.017247. Epub 2020 Jul 29. J Am Heart Assoc. 2020. PMID: 32750288 Free PMC article. No abstract available.
A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer.
Boukouris AE, Zhang Y, Saleme B, Kinnaird A, Zhao YY, Liu Y, Zervopoulos SD, Das SK, Mittal RD, Haromy A, Lorenzana-Carrillo MA, Krysler AR, Cromwell CR, Hubbard BP, Sutendra G, Michelakis ED. Boukouris AE, et al. Among authors: das sk. Cell Rep. 2022 Mar 15;38(11):110511. doi: 10.1016/j.celrep.2022.110511. Cell Rep. 2022. PMID: 35294884 Free article.
Endothelin Receptor Blocker Reverses Breast Cancer-Induced Cardiac Remodeling.
Maayah ZH, Ferdaoussi M, Boukouris AE, Takahara S, Das SK, Khairy M, Mackey JR, Pituskin E, Sutendra G, Paterson DI, Dyck JRB. Maayah ZH, et al. Among authors: das sk. JACC CardioOncol. 2023 May 2;5(5):686-700. doi: 10.1016/j.jaccao.2023.02.004. eCollection 2023 Oct. JACC CardioOncol. 2023. PMID: 37969640 Free PMC article.
Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: a metabolic contribution to heart failure with normal ejection fraction.
Mori J, Basu R, McLean BA, Das SK, Zhang L, Patel VB, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Mori J, et al. Among authors: das sk. Circ Heart Fail. 2012 Jul 1;5(4):493-503. doi: 10.1161/CIRCHEARTFAILURE.112.966705. Epub 2012 Jun 15. Circ Heart Fail. 2012. PMID: 22705769
2,497 results