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Mucosal Vaccination with UV-Inactivated Chlamydia suis in Pre-Exposed Outbred Pigs Decreases Pathogen Load and Induces CD4 T-Cell Maturation into IFN-γ+ Effector Memory Cells.
Amaral AF, Rahman KS, Kick AR, Cortes LM, Robertson J, Kaltenboeck B, Gerdts V, O'Connell CM, Poston TB, Zheng X, Liu C, Omesi SY, Darville T, Käser T. Amaral AF, et al. Among authors: darville t. Vaccines (Basel). 2020 Jul 2;8(3):353. doi: 10.3390/vaccines8030353. Vaccines (Basel). 2020. PMID: 32630694 Free PMC article.
Interleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infection.
Scurlock AM, Frazer LC, Andrews CW Jr, O'Connell CM, Foote IP, Bailey SL, Chandra-Kuntal K, Kolls JK, Darville T. Scurlock AM, et al. Among authors: darville t. Infect Immun. 2011 Mar;79(3):1349-62. doi: 10.1128/IAI.00984-10. Epub 2010 Dec 13. Infect Immun. 2011. PMID: 21149587 Free PMC article.
Frequency of Chlamydia trachomatis-specific T cell interferon-γ and interleukin-17 responses in CD4-enriched peripheral blood mononuclear cells of sexually active adolescent females.
Barral R, Desai R, Zheng X, Frazer LC, Sucato GS, Haggerty CL, O'Connell CM, Zurenski MA, Darville T. Barral R, et al. Among authors: darville t. J Reprod Immunol. 2014 Jun;103:29-37. doi: 10.1016/j.jri.2014.01.002. Epub 2014 Feb 1. J Reprod Immunol. 2014. PMID: 24582738 Free PMC article.
Comparable Genital Tract Infection, Pathology, and Immunity in Rhesus Macaques Inoculated with Wild-Type or Plasmid-Deficient Chlamydia trachomatis Serovar D.
Qu Y, Frazer LC, O'Connell CM, Tarantal AF, Andrews CW Jr, O'Connor SL, Russell AN, Sullivan JE, Poston TB, Vallejo AN, Darville T. Qu Y, et al. Among authors: darville t. Infect Immun. 2015 Oct;83(10):4056-67. doi: 10.1128/IAI.00841-15. Epub 2015 Jul 27. Infect Immun. 2015. PMID: 26216426 Free PMC article.
125 results