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AGTR2 absence or antagonism prevents cystic fibrosis pulmonary manifestations.
Darrah RJ, Jacono FJ, Joshi N, Mitchell AL, Sattar A, Campanaro CK, Litman P, Frey J, Nethery DE, Barbato ES, Hodges CA, Corvol H, Cutting GR, Knowles MR, Strug LJ, Drumm ML. Darrah RJ, et al. J Cyst Fibros. 2019 Jan;18(1):127-134. doi: 10.1016/j.jcf.2018.05.013. Epub 2018 Jun 22. J Cyst Fibros. 2019. PMID: 29937318 Free PMC article.
Beta 2 adrenergic receptor polymorphisms in cystic fibrosis.
Hart MA, Konstan MW, Darrah RJ, Schluchter MD, Storfer-Isser A, Xue L, Londono D, Goddard KA, Drumm ML. Hart MA, et al. Among authors: darrah rj. Pediatr Pulmonol. 2005 Jun;39(6):544-50. doi: 10.1002/ppul.20210. Pediatr Pulmonol. 2005. PMID: 15806595 Clinical Trial.
Genetic modifiers of lung disease in cystic fibrosis.
Drumm ML, Konstan MW, Schluchter MD, Handler A, Pace R, Zou F, Zariwala M, Fargo D, Xu A, Dunn JM, Darrah RJ, Dorfman R, Sandford AJ, Corey M, Zielenski J, Durie P, Goddard K, Yankaskas JR, Wright FA, Knowles MR; Gene Modifier Study Group. Drumm ML, et al. Among authors: darrah rj. N Engl J Med. 2005 Oct 6;353(14):1443-53. doi: 10.1056/NEJMoa051469. N Engl J Med. 2005. PMID: 16207846 Free article.
EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates, and cystic fibrosis pulmonary disease severity.
Darrah R, McKone E, O'Connor C, Rodgers C, Genatossio A, McNamara S, Gibson R, Stuart Elborn J, Ennis M, Gallagher CG, Kalsheker N, Aitken M, Wiese D, Dunn J, Smith P, Pace R, Londono D, Goddard KA, Knowles MR, Drumm ML. Darrah R, et al. Physiol Genomics. 2010 Mar 3;41(1):71-7. doi: 10.1152/physiolgenomics.00185.2009. Epub 2009 Dec 22. Physiol Genomics. 2010. PMID: 20028935 Free PMC article.
Early pulmonary disease manifestations in cystic fibrosis mice.
Darrah RJ, Mitchell AL, Campanaro CK, Barbato ES, Litman P, Sattar A, Hodges CA, Drumm ML, Jacono FJ. Darrah RJ, et al. J Cyst Fibros. 2016 Nov;15(6):736-744. doi: 10.1016/j.jcf.2016.05.002. Epub 2016 May 24. J Cyst Fibros. 2016. PMID: 27231029 Free PMC article.
33 results