Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

8 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
Finlay WJ, Cunningham O, Lambert MA, Darmanin-Sheehan A, Liu X, Fennell BJ, Mahon CM, Cummins E, Wade JM, O'Sullivan CM, Tan XY, Piche N, Pittman DD, Paulsen J, Tchistiakova L, Kodangattil S, Gill D, Hufton SE. Finlay WJ, et al. Among authors: darmanin sheehan a. J Mol Biol. 2009 May 8;388(3):541-58. doi: 10.1016/j.jmb.2009.03.019. Epub 2009 Mar 13. J Mol Biol. 2009. PMID: 19285987
CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery.
Fennell BJ, McDonnell B, Tam AS, Chang L, Steven J, Broadbent ID, Gao H, Kieras E, Alley J, Luxenberg D, Edmonds J, Fitz LJ, Miao W, Whitters MJ, Medley QG, Guo YJ, Darmanin-Sheehan A, Autin B, Shúilleabháin DN, Cummins E, King A, Krebs MR, Grace C, Hickling TP, Boisvert A, Zhong X, McKenna M, Francis C, Olland S, Bloom L, Paulsen J, Somers W, Jensen A, Lin L, Finlay WJ, Cunningham O. Fennell BJ, et al. Among authors: darmanin sheehan a. MAbs. 2013 Nov-Dec;5(6):882-95. doi: 10.4161/mabs.26201. Epub 2013 Aug 21. MAbs. 2013. PMID: 23995618 Free PMC article.
Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies.
Townsend S, Fennell BJ, Apgar JR, Lambert M, McDonnell B, Grant J, Wade J, Franklin E, Foy N, Ní Shúilleabháin D, Fields C, Darmanin-Sheehan A, King A, Paulsen JE, Hickling TP, Tchistiakova L, Cunningham O, Finlay WJ. Townsend S, et al. Among authors: darmanin sheehan a. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15354-9. doi: 10.1073/pnas.1510944112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2015. PMID: 26621728 Free PMC article.
Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis.
O'Dwyer R, Kovaleva M, Zhang J, Steven J, Cummins E, Luxenberg D, Darmanin-Sheehan A, Carvalho MF, Whitters M, Saunders K, Barelle CJ. O'Dwyer R, et al. Among authors: darmanin sheehan a. J Immunol Res. 2018 Oct 17;2018:4089459. doi: 10.1155/2018/4089459. eCollection 2018. J Immunol Res. 2018. PMID: 30417018 Free PMC article.
Fundamental characteristics of the immunoglobulin VH repertoire of chickens in comparison with those of humans, mice, and camelids.
Wu L, Oficjalska K, Lambert M, Fennell BJ, Darmanin-Sheehan A, Ní Shúilleabháin D, Autin B, Cummins E, Tchistiakova L, Bloom L, Paulsen J, Gill D, Cunningham O, Finlay WJ. Wu L, et al. Among authors: darmanin sheehan a. J Immunol. 2012 Jan 1;188(1):322-33. doi: 10.4049/jimmunol.1102466. Epub 2011 Nov 30. J Immunol. 2012. PMID: 22131336