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Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Sandusky-Beltran LA, Kovalenko A, Placides DS, Ratnasamy K, Ma C, Hunt JB Jr, Liang H, Calahatian JIT, Michalski C, Fahnestock M, Blair LJ, Darling AL, Baker JD, Fontaine SN, Dickey CA, Gamsby JJ, Nash KR, Abner E, Selenica MB, Lee DC. Sandusky-Beltran LA, et al. Among authors: darling al. J Clin Invest. 2021 Feb 15;131(4):e126299. doi: 10.1172/JCI126299. J Clin Invest. 2021. PMID: 33586680 Free PMC article.
Cellular factors modulating the mechanism of tau protein aggregation.
Fontaine SN, Sabbagh JJ, Baker J, Martinez-Licha CR, Darling A, Dickey CA. Fontaine SN, et al. Cell Mol Life Sci. 2015 May;72(10):1863-79. doi: 10.1007/s00018-015-1839-9. Epub 2015 Feb 11. Cell Mol Life Sci. 2015. PMID: 25666877 Free PMC article. Review.
Human cyclophilin 40 unravels neurotoxic amyloids.
Baker JD, Shelton LB, Zheng D, Favretto F, Nordhues BA, Darling A, Sullivan LE, Sun Z, Solanki PK, Martin MD, Suntharalingam A, Sabbagh JJ, Becker S, Mandelkow E, Uversky VN, Zweckstetter M, Dickey CA, Koren J 3rd, Blair LJ. Baker JD, et al. PLoS Biol. 2017 Jun 27;15(6):e2001336. doi: 10.1371/journal.pbio.2001336. eCollection 2017 Jun. PLoS Biol. 2017. PMID: 28654636 Free PMC article.
Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.
Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J 3rd, Dickey CA, Blair LJ. Sabbagh JJ, et al. Among authors: darling al. ACS Chem Biol. 2018 Aug 17;13(8):2288-2299. doi: 10.1021/acschembio.8b00454. Epub 2018 Jun 19. ACS Chem Biol. 2018. PMID: 29893552 Free PMC article.
Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Sandusky-Beltran LA, Kovalenko A, Ma C, Calahatian JIT, Placides DS, Watler MD, Hunt JB, Darling AL, Baker JD, Blair LJ, Martin MD, Fontaine SN, Dickey CA, Lussier AL, Weeber EJ, Selenica MB, Nash KR, Gordon MN, Morgan D, Lee DC. Sandusky-Beltran LA, et al. Among authors: darling al. Alzheimers Res Ther. 2019 Jun 29;11(1):58. doi: 10.1186/s13195-019-0507-y. Alzheimers Res Ther. 2019. PMID: 31253191 Free PMC article.
57 results