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Autophagy is a novel pathway for neurofilament protein degradation in vivo.
Rao MV, Darji S, Stavrides PH, Goulbourne CN, Kumar A, Yang DS, Yoo L, Peddy J, Lee JH, Yuan A, Nixon RA. Rao MV, et al. Among authors: darji s. Autophagy. 2023 Apr;19(4):1277-1292. doi: 10.1080/15548627.2022.2124500. Epub 2022 Sep 21. Autophagy. 2023. PMID: 36131358 Free PMC article.
Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.
Jiang Y, Alam JJ, Gomperts SN, Maruff P, Lemstra AW, Germann UA, Stavrides PH, Darji S, Malampati S, Peddy J, Bleiwas C, Pawlik M, Pensalfini A, Yang DS, Subbanna S, Basavarajappa BS, Smiley JF, Gardner A, Blackburn K, Chu HM, Prins ND, Teunissen CE, Harrison JE, Scheltens P, Nixon RA. Jiang Y, et al. Among authors: darji s. Nat Commun. 2022 Sep 21;13(1):5308. doi: 10.1038/s41467-022-32944-3. Nat Commun. 2022. PMID: 36130946 Free PMC article. Clinical Trial.
Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease.
Pensalfini A, Kim S, Subbanna S, Bleiwas C, Goulbourne CN, Stavrides PH, Jiang Y, Lee JH, Darji S, Pawlik M, Huo C, Peddy J, Berg MJ, Smiley JF, Basavarajappa BS, Nixon RA. Pensalfini A, et al. Among authors: darji s. Cell Rep. 2020 Nov 24;33(8):108420. doi: 10.1016/j.celrep.2020.108420. Cell Rep. 2020. PMID: 33238112 Free PMC article.
20 results