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Dimethyl fumarate and vitamin D derivatives cooperatively enhance VDR and Nrf2 signaling in differentiating AML cells in vitro and inhibit leukemia progression in a xenograft mouse model.
Nachliely M, Trachtenberg A, Khalfin B, Nalbandyan K, Cohen-Lahav M, Yasuda K, Sakaki T, Kutner A, Danilenko M. Nachliely M, et al. Among authors: danilenko m. J Steroid Biochem Mol Biol. 2019 Apr;188:8-16. doi: 10.1016/j.jsbmb.2018.11.017. Epub 2018 Nov 30. J Steroid Biochem Mol Biol. 2019. PMID: 30508646
Carnosic acid potentiates the antioxidant and prodifferentiation effects of 1alpha,25-dihydroxyvitamin D3 in leukemia cells but does not promote elevation of basal levels of intracellular calcium.
Danilenko M, Wang Q, Wang X, Levy J, Sharoni Y, Studzinski GP. Danilenko M, et al. Cancer Res. 2003 Mar 15;63(6):1325-32. Cancer Res. 2003. PMID: 12649194
We have recently used the plant-derived polyphenolic antioxidant, carnosic acid (CA), to demonstrate an increase in the differentiating action of 1,25D(3) on human leukemia cells under these conditions (M. Danilenko et al., JNCI, 93: 1224-1233, 2001). We now show th …
We have recently used the plant-derived polyphenolic antioxidant, carnosic acid (CA), to demonstrate an increase in the differentiating acti …
175 results