Daniella Zheleva - Search Results

Year	Number of Results
2002	3
2003	4
2004	1
2005	2
2006	1
2008	1
2010	4
2011	1
2012	1
2015	1
2019	1
2020	2
2021	2
2022	1
2024	0

1

Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells.

Chen R, Chen Y, Xiong P, Zheleva D, Blake D, Keating MJ, Wierda WG, Plunkett W. Chen R, et al. Among authors: zheleva d. Leukemia. 2022 Jun;36(6):1596-1608. doi: 10.1038/s41375-022-01553-w. Epub 2022 Apr 5. Leukemia. 2022. PMID: 35383271 Free PMC article.

2

Correction to: Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML.

Chantkran W, Hsieh YC, Zheleva D, Frame S, Wheadon H, Copland M. Chantkran W, et al. Among authors: zheleva d. Cell Death Discov. 2021 Jul 6;7(1):171. doi: 10.1038/s41420-021-00558-1. Cell Death Discov. 2021. PMID: 34230455 Free PMC article. No abstract available.

3

Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML.

Chantkran W, Hsieh YC, Zheleva D, Frame S, Wheadon H, Copland M. Chantkran W, et al. Among authors: zheleva d. Cell Death Discov. 2021 Jun 10;7(1):137. doi: 10.1038/s41420-021-00496-y. Cell Death Discov. 2021. PMID: 34112754 Free PMC article.

4

Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma.

Poon E, Liang T, Jamin Y, Walz S, Kwok C, Hakkert A, Barker K, Urban Z, Thway K, Zeid R, Hallsworth A, Box G, Ebus ME, Licciardello MP, Sbirkov Y, Lazaro G, Calton E, Costa BM, Valenti M, De Haven Brandon A, Webber H, Tardif N, Almeida GS, Christova R, Boysen G, Richards MW, Barone G, Ford A, Bayliss R, Clarke PA, De Bono J, Gray NS, Blagg J, Robinson SP, Eccles SA, Zheleva D, Bradner JE, Molenaar J, Vivanco I, Eilers M, Workman P, Lin CY, Chesler L. Poon E, et al. Among authors: zheleva d. J Clin Invest. 2020 Nov 2;130(11):5875-5892. doi: 10.1172/JCI134132. J Clin Invest. 2020. PMID: 33016930 Free PMC article.

5

Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer.

Frame S, Saladino C, MacKay C, Atrash B, Sheldrake P, McDonald E, Clarke PA, Workman P, Blake D, Zheleva D. Frame S, et al. Among authors: zheleva d. PLoS One. 2020 Jul 9;15(7):e0234103. doi: 10.1371/journal.pone.0234103. eCollection 2020. PLoS One. 2020. PMID: 32645016 Free PMC article.

6

Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma.

Noonan JJ, Jarzabek M, Lincoln FA, Cavanagh BL, Pariag AR, Juric V, Young LS, Ligon KL, Jahns H, Zheleva D, Prehn JHM, Rehm M, Byrne AT, Murphy BM. Noonan JJ, et al. Among authors: zheleva d. Cancers (Basel). 2019 Dec 12;11(12):2005. doi: 10.3390/cancers11122005. Cancers (Basel). 2019. PMID: 31842413 Free PMC article.

7

Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1.

Aspinall CF, Zheleva D, Tighe A, Taylor SS. Aspinall CF, et al. Among authors: zheleva d. Oncotarget. 2015 Nov 3;6(34):36472-88. doi: 10.18632/oncotarget.5507. Oncotarget. 2015. PMID: 26472023 Free PMC article.

8

Aurora kinase inhibitors: progress towards the clinic.

Kollareddy M, Zheleva D, Dzubak P, Brahmkshatriya PS, Lepsik M, Hajduch M. Kollareddy M, et al. Among authors: zheleva d. Invest New Drugs. 2012 Dec;30(6):2411-32. doi: 10.1007/s10637-012-9798-6. Epub 2012 Feb 18. Invest New Drugs. 2012. PMID: 22350019 Free PMC article. Review.

9

A novel cell-based, high-content assay for phosphorylation of Lats2 by Aurora A.

Emery A, Sorrell DA, Lawrence S, Easthope E, Stockdale M, Jones DO, Zheleva D, Scaerou F, Glover DM. Emery A, et al. Among authors: zheleva d. J Biomol Screen. 2011 Sep;16(8):925-31. doi: 10.1177/1087057111413923. Epub 2011 Jul 25. J Biomol Screen. 2011. PMID: 21788394

10

Discovery and characterization of 2-anilino-4- (thiazol-5-yl)pyrimidine transcriptional CDK inhibitors as anticancer agents.

Wang S, Griffiths G, Midgley CA, Barnett AL, Cooper M, Grabarek J, Ingram L, Jackson W, Kontopidis G, McClue SJ, McInnes C, McLachlan J, Meades C, Mezna M, Stuart I, Thomas MP, Zheleva DI, Lane DP, Jackson RC, Glover DM, Blake DG, Fischer PM. Wang S, et al. Among authors: zheleva di. Chem Biol. 2010 Oct 29;17(10):1111-21. doi: 10.1016/j.chembiol.2010.07.016. Chem Biol. 2010. PMID: 21035734

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