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Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models.
Crouzier L, Danese A, Yasui Y, Richard EM, Liévens JC, Patergnani S, Couly S, Diez C, Denus M, Cubedo N, Rossel M, Thiry M, Su TP, Pinton P, Maurice T, Delprat B. Crouzier L, et al. Among authors: danese a. Sci Transl Med. 2022 Feb 9;14(631):eabh3763. doi: 10.1126/scitranslmed.abh3763. Epub 2022 Feb 9. Sci Transl Med. 2022. PMID: 35138910 Free PMC article.
Endoplasmic reticulum-mitochondria Ca2+ crosstalk in the control of the tumor cell fate.
Missiroli S, Danese A, Iannitti T, Patergnani S, Perrone M, Previati M, Giorgi C, Pinton P. Missiroli S, et al. Among authors: danese a. Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):858-864. doi: 10.1016/j.bbamcr.2016.12.024. Epub 2017 Jan 4. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28064002 Free article. Review.
BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation.
Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, Pellegrini L, Signorato V, Olivetto F, Pastorino S, Nasu M, Napolitano A, Gaudino G, Morris P, Sakamoto G, Ferris LK, Danese A, Raimondi A, Tacchetti C, Kuchay S, Pass HI, Affar EB, Yang H, Pinton P, Carbone M. Bononi A, et al. Among authors: danese a. Nature. 2017 Jun 22;546(7659):549-553. doi: 10.1038/nature22798. Epub 2017 Jun 14. Nature. 2017. PMID: 28614305 Free PMC article.
Calcium Dynamics as a Machine for Decoding Signals.
Giorgi C, Danese A, Missiroli S, Patergnani S, Pinton P. Giorgi C, et al. Among authors: danese a. Trends Cell Biol. 2018 Apr;28(4):258-273. doi: 10.1016/j.tcb.2018.01.002. Epub 2018 Feb 3. Trends Cell Biol. 2018. PMID: 29409699 Review.
Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.
Morciano G, Marchi S, Morganti C, Sbano L, Bittremieux M, Kerkhofs M, Corricelli M, Danese A, Karkucinska-Wieckowska A, Wieckowski MR, Bultynck G, Giorgi C, Pinton P. Morciano G, et al. Among authors: danese a. Neoplasia. 2018 May;20(5):510-523. doi: 10.1016/j.neo.2018.03.005. Epub 2018 Apr 5. Neoplasia. 2018. PMID: 29626751 Free PMC article. Review.
ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome.
Angebault C, Fauconnier J, Patergnani S, Rieusset J, Danese A, Affortit CA, Jagodzinska J, Mégy C, Quiles M, Cazevieille C, Korchagina J, Bonnet-Wersinger D, Milea D, Hamel C, Pinton P, Thiry M, Lacampagne A, Delprat B, Delettre C. Angebault C, et al. Among authors: danese a. Sci Signal. 2018 Oct 23;11(553):eaaq1380. doi: 10.1126/scisignal.aaq1380. Sci Signal. 2018. PMID: 30352948 Free article.
Mitochondrial calcium uniporter complex modulation in cancerogenesis.
Marchi S, Vitto VAM, Danese A, Wieckowski MR, Giorgi C, Pinton P. Marchi S, et al. Among authors: danese a. Cell Cycle. 2019 May;18(10):1068-1083. doi: 10.1080/15384101.2019.1612698. Epub 2019 May 10. Cell Cycle. 2019. PMID: 31032692 Free PMC article. Review.
Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome.
La Morgia C, Maresca A, Amore G, Gramegna LL, Carbonelli M, Scimonelli E, Danese A, Patergnani S, Caporali L, Tagliavini F, Del Dotto V, Capristo M, Sadun F, Barboni P, Savini G, Evangelisti S, Bianchini C, Valentino ML, Liguori R, Tonon C, Giorgi C, Pinton P, Lodi R, Carelli V. La Morgia C, et al. Among authors: danese a. Sci Rep. 2020 Mar 16;10(1):4785. doi: 10.1038/s41598-020-61735-3. Sci Rep. 2020. PMID: 32179840 Free PMC article.
Author Correction: Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome.
La Morgia C, Maresca A, Amore G, Gramegna LL, Carbonelli M, Scimonelli E, Danese A, Patergnani S, Caporali L, Tagliavini F, Del Dotto V, Capristo M, Sadun F, Barboni P, Savini G, Evangelisti S, Bianchini C, Valentino ML, Liguori R, Tonon C, Giorgi C, Pinton P, Lodi R, Carelli V. La Morgia C, et al. Among authors: danese a. Sci Rep. 2020 Jun 23;10(1):10398. doi: 10.1038/s41598-020-67203-2. Sci Rep. 2020. PMID: 32576919 Free PMC article.
217 results