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A broad-spectrum antiviral targeting entry of enveloped viruses.
Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. Wolf MC, et al. Among authors: damoiseaux r. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. doi: 10.1073/pnas.0909587107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133606 Free PMC article.
Nonaminoglycoside compounds induce readthrough of nonsense mutations.
Du L, Damoiseaux R, Nahas S, Gao K, Hu H, Pollard JM, Goldstine J, Jung ME, Henning SM, Bertoni C, Gatti RA. Du L, et al. Among authors: damoiseaux r. J Exp Med. 2009 Sep 28;206(10):2285-97. doi: 10.1084/jem.20081940. Epub 2009 Sep 21. J Exp Med. 2009. PMID: 19770270 Free PMC article.
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase.
Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J. Aghajan M, et al. Among authors: damoiseaux r. Nat Biotechnol. 2010 Jul;28(7):738-42. doi: 10.1038/nbt.1645. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581845 Free PMC article.
Fluoxetine is a potent inhibitor of coxsackievirus replication.
Zuo J, Quinn KK, Kye S, Cooper P, Damoiseaux R, Krogstad P. Zuo J, et al. Among authors: damoiseaux r. Antimicrob Agents Chemother. 2012 Sep;56(9):4838-44. doi: 10.1128/AAC.00983-12. Epub 2012 Jul 2. Antimicrob Agents Chemother. 2012. PMID: 22751539 Free PMC article.
Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal.
Tsirulnikov K, Abuladze N, Bragin A, Faull K, Cascio D, Damoiseaux R, Schibler MJ, Pushkin A. Tsirulnikov K, et al. Among authors: damoiseaux r. Toxicol Appl Pharmacol. 2012 Sep 15;263(3):303-14. doi: 10.1016/j.taap.2012.07.002. Epub 2012 Jul 20. Toxicol Appl Pharmacol. 2012. PMID: 22819785 Free PMC article.
269 results