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Page 1
Manufactured nanomaterials: categorization and approaches to hazard assessment.
Gebel T, Foth H, Damm G, Freyberger A, Kramer PJ, Lilienblum W, Röhl C, Schupp T, Weiss C, Wollin KM, Hengstler JG. Gebel T, et al. Among authors: damm g. Arch Toxicol. 2014 Dec;88(12):2191-211. doi: 10.1007/s00204-014-1383-7. Epub 2014 Oct 19. Arch Toxicol. 2014. PMID: 25326817 Review.
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG. Godoy P, et al. Among authors: damm g. Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Arch Toxicol. 2013. PMID: 23974980 Free PMC article. Review.
Toxicogenomics directory of chemically exposed human hepatocytes.
Grinberg M, Stöber RM, Edlund K, Rempel E, Godoy P, Reif R, Widera A, Madjar K, Schmidt-Heck W, Marchan R, Sachinidis A, Spitkovsky D, Hescheler J, Carmo H, Arbo MD, van de Water B, Wink S, Vinken M, Rogiers V, Escher S, Hardy B, Mitic D, Myatt G, Waldmann T, Mardinoglu A, Damm G, Seehofer D, Nüssler A, Weiss TS, Oberemm A, Lampen A, Schaap MM, Luijten M, van Steeg H, Thasler WE, Kleinjans JC, Stierum RH, Leist M, Rahnenführer J, Hengstler JG. Grinberg M, et al. Among authors: damm g. Arch Toxicol. 2014 Dec;88(12):2261-87. doi: 10.1007/s00204-014-1400-x. Epub 2014 Nov 16. Arch Toxicol. 2014. PMID: 25399406
High exposure to inorganic arsenic by food: the need for risk reduction.
Gundert-Remy U, Damm G, Foth H, Freyberger A, Gebel T, Golka K, Röhl C, Schupp T, Wollin KM, Hengstler JG. Gundert-Remy U, et al. Among authors: damm g. Arch Toxicol. 2015 Dec;89(12):2219-27. doi: 10.1007/s00204-015-1627-1. Epub 2015 Nov 19. Arch Toxicol. 2015. PMID: 26586021 Review.
Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition.
Deharde D, Schneider C, Hiller T, Fischer N, Kegel V, Lübberstedt M, Freyer N, Hengstler JG, Andersson TB, Seehofer D, Pratschke J, Zeilinger K, Damm G. Deharde D, et al. Among authors: damm g. Arch Toxicol. 2016 Oct;90(10):2497-511. doi: 10.1007/s00204-016-1758-z. Epub 2016 Jun 21. Arch Toxicol. 2016. PMID: 27325308
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.
Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG. Godoy P, et al. Among authors: damm g. Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23. Arch Toxicol. 2016. PMID: 27339419 Free PMC article.
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Albrecht W, Kappenberg F, Brecklinghaus T, Stoeber R, Marchan R, Zhang M, Ebbert K, Kirschner H, Grinberg M, Leist M, Moritz W, Cadenas C, Ghallab A, Reinders J, Vartak N, van Thriel C, Golka K, Tolosa L, Castell JV, Damm G, Seehofer D, Lampen A, Braeuning A, Buhrke T, Behr AC, Oberemm A, Gu X, Kittana N, van de Water B, Kreiling R, Fayyaz S, van Aerts L, Smedsrød B, Ellinger-Ziegelbauer H, Steger-Hartmann T, Gundert-Remy U, Zeigerer A, Ullrich A, Runge D, Lee SML, Schiergens TS, Kuepfer L, Aguayo-Orozco A, Sachinidis A, Edlund K, Gardner I, Rahnenführer J, Hengstler JG. Albrecht W, et al. Among authors: damm g. Arch Toxicol. 2019 Jun;93(6):1609-1637. doi: 10.1007/s00204-019-02492-9. Epub 2019 Jun 27. Arch Toxicol. 2019. PMID: 31250071
120 results