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Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity.
Pinto-Fernandez A, Salio M, Partridge T, Chen J, Vere G, Greenwood H, Olie CS, Damianou A, Scott HC, Pegg HJ, Chiarenza A, Díaz-Saez L, Smith P, Gonzalez-Lopez C, Patel B, Anderton E, Jones N, Hammonds TR, Huber K, Muschel R, Borrow P, Cerundolo V, Kessler BM. Pinto-Fernandez A, et al. Among authors: damianou a. Br J Cancer. 2021 Feb;124(4):817-830. doi: 10.1038/s41416-020-01167-y. Epub 2020 Nov 20. Br J Cancer. 2021. PMID: 33214684 Free PMC article.
USP18 is an essential regulator of muscle cell differentiation and maturation.
Olie CS, Pinto-Fernández A, Damianou A, Vendrell I, Mei H, den Hamer B, van der Wal E, de Greef JC, Raz V, Kessler BM. Olie CS, et al. Among authors: damianou a. Cell Death Dis. 2023 Mar 31;14(3):231. doi: 10.1038/s41419-023-05725-z. Cell Death Dis. 2023. PMID: 37002195 Free PMC article.
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma.
Ruiz EJ, Pinto-Fernandez A, Turnbull AP, Lan L, Charlton TM, Scott HC, Damianou A, Vere G, Riising EM, Da Costa C, Krajewski WW, Guerin D, Kearns JD, Ioannidis S, Katz M, McKinnon C, O'Connell J, Moncaut N, Rosewell I, Nye E, Jones N, Heride C, Gersch M, Wu M, Dinsmore CJ, Hammonds TR, Kim S, Komander D, Urbe S, Clague MJ, Kessler BM, Behrens A. Ruiz EJ, et al. Among authors: damianou a. Elife. 2021 Oct 12;10:e71596. doi: 10.7554/eLife.71596. Elife. 2021. PMID: 34636321 Free PMC article.
Essential roles for deubiquitination in Leishmania life cycle progression.
Damianou A, Burge RJ, Catta-Preta CMC, Geoghegan V, Nievas YR, Newling K, Brown E, Burchmore R, Rodenko B, Mottram JC. Damianou A, et al. PLoS Pathog. 2020 Jun 16;16(6):e1008455. doi: 10.1371/journal.ppat.1008455. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32544189 Free PMC article.
Deubiquitinases in muscle physiology and disorders.
Olie CS, O'Brien DP, Jones HBL, Liang Z, Damianou A, Sur-Erdem I, Pinto-Fernández A, Raz V, Kessler BM. Olie CS, et al. Among authors: damianou a. Biochem Soc Trans. 2024 May 8:BST20230562. doi: 10.1042/BST20230562. Online ahead of print. Biochem Soc Trans. 2024. PMID: 38716888
16 results