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Stromal SPOCK1 supports invasive pancreatic cancer growth.
Veenstra VL, Damhofer H, Waasdorp C, Steins A, Kocher HM, Medema JP, van Laarhoven HW, Bijlsma MF. Veenstra VL, et al. Among authors: damhofer h. Mol Oncol. 2017 Aug;11(8):1050-1064. doi: 10.1002/1878-0261.12073. Epub 2017 Jun 5. Mol Oncol. 2017. PMID: 28486750 Free PMC article.
Patched-2 functions to limit Patched-1 deficient skin cancer growth.
Veenstra VL, Dingjan I, Waasdorp C, Damhofer H, van der Wal AC, van Laarhoven HW, Medema JP, Bijlsma MF. Veenstra VL, et al. Among authors: damhofer h. Cell Oncol (Dordr). 2018 Aug;41(4):427-437. doi: 10.1007/s13402-018-0381-9. Epub 2018 Jun 4. Cell Oncol (Dordr). 2018. PMID: 29869097 Free PMC article.
ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy.
Veenstra VL, Damhofer H, Waasdorp C, van Rijssen LB, van de Vijver MJ, Dijk F, Wilmink HW, Besselink MG, Busch OR, Chang DK, Bailey PJ, Biankin AV, Kocher HM, Medema JP, Li JS, Jiang R, Pierce DW, van Laarhoven HWM, Bijlsma MF. Veenstra VL, et al. Among authors: damhofer h. Oncogenesis. 2018 Nov 16;7(11):87. doi: 10.1038/s41389-018-0096-9. Oncogenesis. 2018. PMID: 30442938 Free PMC article.
Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract.
Damhofer H, Ebbing EA, Steins A, Welling L, Tol JA, Krishnadath KK, van Leusden T, van de Vijver MJ, Besselink MG, Busch OR, van Berge Henegouwen MI, van Delden O, Meijer SL, Dijk F, Medema JP, van Laarhoven HW, Bijlsma MF. Damhofer H, et al. J Transl Med. 2015 Apr 11;13:115. doi: 10.1186/s12967-015-0469-1. J Transl Med. 2015. PMID: 25884700 Free PMC article.
Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems.
Dijk F, Veenstra VL, Soer EC, Dings MPG, Zhao L, Halfwerk JB, Hooijer GK, Damhofer H, Marzano M, Steins A, Waasdorp C, Busch OR, Besselink MG, Tol JA, Welling L, van Rijssen LB, Klompmaker S, Wilmink HW, van Laarhoven HW, Medema JP, Vermeulen L, van Hooff SR, Koster J, Verheij J, van de Vijver MJ, Wang X, Bijlsma MF. Dijk F, et al. Among authors: damhofer h. Sci Rep. 2020 Jan 15;10(1):337. doi: 10.1038/s41598-019-56826-9. Sci Rep. 2020. PMID: 31941932 Free PMC article.
Serum-based measurements of stromal activation through ADAM12 associate with poor prognosis in colorectal cancer.
Ten Hoorn S, Waasdorp C, van Oijen MGH, Damhofer H, Trinh A, Zhao L, Smits LJH, Bootsma S, van Pelt GW, Mesker WE, Mol L, Goey KKH, Koopman M, Medema JP, Tuynman JB, Zlobec I, Punt CJA, Vermeulen L, Bijlsma MF. Ten Hoorn S, et al. Among authors: damhofer h. BMC Cancer. 2022 Apr 12;22(1):394. doi: 10.1186/s12885-022-09436-0. BMC Cancer. 2022. PMID: 35413826 Free PMC article.
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