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Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection.
Cwiklinski K, McEvoy A, López Corrales J, Jewhurst H, Calvani NED, De Marco Verissimo C, Dorey AL, Keane OM, Dalton JP, Lalor R. Cwiklinski K, et al. Among authors: dalton jp. Vet Parasitol. 2023 Oct 8;323:110049. doi: 10.1016/j.vetpar.2023.110049. Online ahead of print. Vet Parasitol. 2023. PMID: 37826973 Free article.
A new multiplex SARS-CoV-2 antigen microarray showed correlation of IgG, IgA, and IgM antibodies from patients with COVID-19 disease severity and maintenance of relative IgA and IgM antigen binding over time.
Berre ML, Paulovčáková T, Verissimo CM, Doyle S, Dalton JP, Masterson C, Martínez ER, Walsh L, Gormley C, Laffey JG, McNicholas B, Simpkin AJ, Kilcoyne M. Berre ML, et al. Among authors: dalton jp. PLoS One. 2023 Mar 30;18(3):e0283537. doi: 10.1371/journal.pone.0283537. eCollection 2023. PLoS One. 2023. PMID: 36996259 Free PMC article.
Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during Growth and Development.
Calvani NED, De Marco Verissimo C, Jewhurst HL, Cwiklinski K, Flaus A, Dalton JP. Calvani NED, et al. Among authors: dalton jp. Antioxidants (Basel). 2022 Sep 30;11(10):1968. doi: 10.3390/antiox11101968. Antioxidants (Basel). 2022. PMID: 36290692 Free PMC article.
Omics tools enabling vaccine discovery against fasciolosis.
Cwiklinski K, Dalton JP. Cwiklinski K, et al. Among authors: dalton jp. Trends Parasitol. 2022 Dec;38(12):1068-1079. doi: 10.1016/j.pt.2022.09.009. Epub 2022 Oct 18. Trends Parasitol. 2022. PMID: 36270885 Free article. Review.
Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system.
De Marco Verissimo C, López Corrales J, Dorey AL, Cwiklinski K, Lalor R, Calvani NED, Jewhurst HL, Flaus A, Doyle S, Dalton JP. De Marco Verissimo C, et al. Among authors: dalton jp. Epidemiol Infect. 2022 Jun 20;150:e128. doi: 10.1017/S0950268822001078. Epidemiol Infect. 2022. PMID: 35723031 Free PMC article.
244 results