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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ. Shen C, et al. Among authors: dakshanamurthy s. Nat Commun. 2021 Sep 6;12(1):5263. doi: 10.1038/s41467-021-25634-z. Nat Commun. 2021. PMID: 34489457 Free PMC article.
A novel chemo-phenotypic method identifies mixtures of salpn, vitamin D3, and pesticides involved in the development of colorectal and pancreatic cancer.
Issa NT, Wathieu H, Glasgow E, Peran I, Parasido E, Li T, Simbulan-Rosenthal CM, Rosenthal D, Medvedev AV, Makarov SS, Albanese C, Byers SW, Dakshanamurthy S. Issa NT, et al. Among authors: dakshanamurthy s. Ecotoxicol Environ Saf. 2022 Mar 15;233:113330. doi: 10.1016/j.ecoenv.2022.113330. Epub 2022 Feb 19. Ecotoxicol Environ Saf. 2022. PMID: 35189517 Free PMC article.
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.
Petrini I, Meltzer PS, Kim IK, Lucchi M, Park KS, Fontanini G, Gao J, Zucali PA, Calabrese F, Favaretto A, Rea F, Rodriguez-Canales J, Walker RL, Pineda M, Zhu YJ, Lau C, Killian KJ, Bilke S, Voeller D, Dakshanamurthy S, Wang Y, Giaccone G. Petrini I, et al. Among authors: dakshanamurthy s. Nat Genet. 2014 Aug;46(8):844-9. doi: 10.1038/ng.3016. Epub 2014 Jun 29. Nat Genet. 2014. PMID: 24974848 Free PMC article.
75 results