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Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories.
van Gastel J, Cai H, Cong WN, Chadwick W, Daimon C, Leysen H, Hendrickx JO, De Schepper R, Vangenechten L, Van Turnhout J, Verswyvel J, Becker KG, Zhang Y, Lehrmann E, Wood WH 3rd, Martin B, Maudsley S. van Gastel J, et al. Among authors: daimon c. Mech Ageing Dev. 2019 Dec;184:111150. doi: 10.1016/j.mad.2019.111150. Epub 2019 Sep 28. Mech Ageing Dev. 2019. PMID: 31574270
Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption.
Siddiqui S, Lustig A, Carter A, Sankar M, Daimon CM, Premont RT, Etienne H, van Gastel J, Azmi A, Janssens J, Becker KG, Zhang Y, Wood W, Lehrmann E, Martin JG, Martin B, Taub DD, Maudsley S. Siddiqui S, et al. Among authors: daimon cm. Aging (Albany NY). 2017 Mar 4;9(3):706-740. doi: 10.18632/aging.101185. Aging (Albany NY). 2017. PMID: 28260693 Free PMC article.
Nuclear GIT2 is an ATM substrate and promotes DNA repair.
Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S. Lu D, et al. Mol Cell Biol. 2015 Apr;35(7):1081-96. doi: 10.1128/MCB.01432-14. Epub 2015 Jan 20. Mol Cell Biol. 2015. PMID: 25605334 Free PMC article.
GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.
Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S. Martin B, et al. Among authors: daimon cm. Front Endocrinol (Lausanne). 2016 Jan 18;6:191. doi: 10.3389/fendo.2015.00191. eCollection 2015. Front Endocrinol (Lausanne). 2016. PMID: 26834700 Free PMC article.
29 results