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Non-peptide AT2-receptor agonists.
Steckelings UM, Larhed M, Hallberg A, Widdop RE, Jones ES, Wallinder C, Namsolleck P, Dahlöf B, Unger T. Steckelings UM, et al. Among authors: dahlof b. Curr Opin Pharmacol. 2011 Apr;11(2):187-92. doi: 10.1016/j.coph.2010.11.002. Epub 2010 Dec 15. Curr Opin Pharmacol. 2011. PMID: 21167778 Review.
Angiotensin AT2-receptor stimulation improves survival and neurological outcome after experimental stroke in mice.
Schwengel K, Namsolleck P, Lucht K, Clausen BH, Lambertsen KL, Valero-Esquitino V, Thöne-Reineke C, Müller S, Widdop RE, Denton KM, Horiuchi M, Iwai M, Boato F, Dahlöf B, Hallberg A, Unger T, Steckelings UM. Schwengel K, et al. Among authors: dahlof b. J Mol Med (Berl). 2016 Aug;94(8):957-66. doi: 10.1007/s00109-016-1406-3. Epub 2016 Mar 16. J Mol Med (Berl). 2016. PMID: 26983606
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB.
Rompe F, Artuc M, Hallberg A, Alterman M, Ströder K, Thöne-Reineke C, Reichenbach A, Schacherl J, Dahlöf B, Bader M, Alenina N, Schwaninger M, Zuberbier T, Funke-Kaiser H, Schmidt C, Schunck WH, Unger T, Steckelings UM. Rompe F, et al. Among authors: dahlof b. Hypertension. 2010 Apr;55(4):924-31. doi: 10.1161/HYPERTENSIONAHA.109.147843. Epub 2010 Feb 15. Hypertension. 2010. PMID: 20157051
Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling.
Paulis L, Becker ST, Lucht K, Schwengel K, Slavic S, Kaschina E, Thöne-Reineke C, Dahlöf B, Baulmann J, Unger T, Steckelings UM. Paulis L, et al. Among authors: dahlof b. Hypertension. 2012 Feb;59(2):485-92. doi: 10.1161/HYPERTENSIONAHA.111.185496. Epub 2012 Jan 3. Hypertension. 2012. PMID: 22215717
Angiotensin type 2 receptor stimulation ameliorates left ventricular fibrosis and dysfunction via regulation of tissue inhibitor of matrix metalloproteinase 1/matrix metalloproteinase 9 axis and transforming growth factor β1 in the rat heart.
Lauer D, Slavic S, Sommerfeld M, Thöne-Reineke C, Sharkovska Y, Hallberg A, Dahlöf B, Kintscher U, Unger T, Steckelings UM, Kaschina E. Lauer D, et al. Among authors: dahlof b. Hypertension. 2014 Mar;63(3):e60-7. doi: 10.1161/HYPERTENSIONAHA.113.02522. Epub 2013 Dec 30. Hypertension. 2014. PMID: 24379181 Free article.
Direct angiotensin type 2 receptor (AT2R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice.
Valero-Esquitino V, Lucht K, Namsolleck P, Monnet-Tschudi F, Stubbe T, Lucht F, Liu M, Ebner F, Brandt C, Danyel LA, Villela DC, Paulis L, Thoene-Reineke C, Dahlöf B, Hallberg A, Unger T, Sumners C, Steckelings UM. Valero-Esquitino V, et al. Among authors: dahlof b. Clin Sci (Lond). 2015 Jan;128(2):95-109. doi: 10.1042/CS20130601. Clin Sci (Lond). 2015. PMID: 25052203
Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?
Kaschina E, Grzesiak A, Li J, Foryst-Ludwig A, Timm M, Rompe F, Sommerfeld M, Kemnitz UR, Curato C, Namsolleck P, Tschöpe C, Hallberg A, Alterman M, Hucko T, Paetsch I, Dietrich T, Schnackenburg B, Graf K, Dahlöf B, Kintscher U, Unger T, Steckelings UM. Kaschina E, et al. Among authors: dahlof b. Circulation. 2008 Dec 9;118(24):2523-32. doi: 10.1161/CIRCULATIONAHA.108.784868. Epub 2008 Nov 24. Circulation. 2008. PMID: 19029468
Direct stimulation of angiotensin II type 2 receptor enhances spatial memory.
Jing F, Mogi M, Sakata A, Iwanami J, Tsukuda K, Ohshima K, Min LJ, Steckelings UM, Unger T, Dahlöf B, Horiuchi M. Jing F, et al. Among authors: dahlof b. J Cereb Blood Flow Metab. 2012 Feb;32(2):248-55. doi: 10.1038/jcbfm.2011.133. Epub 2011 Oct 5. J Cereb Blood Flow Metab. 2012. PMID: 21971355 Free PMC article.
399 results