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Inactivation of TNF signaling by rationally designed dominant-negative TNF variants.
Steed PM, Tansey MG, Zalevsky J, Zhukovsky EA, Desjarlais JR, Szymkowski DE, Abbott C, Carmichael D, Chan C, Cherry L, Cheung P, Chirino AJ, Chung HH, Doberstein SK, Eivazi A, Filikov AV, Gao SX, Hubert RS, Hwang M, Hyun L, Kashi S, Kim A, Kim E, Kung J, Martinez SP, Muchhal US, Nguyen DH, O'Brien C, O'Keefe D, Singer K, Vafa O, Vielmetter J, Yoder SC, Dahiyat BI. Steed PM, et al. Among authors: dahiyat bi. Science. 2003 Sep 26;301(5641):1895-8. doi: 10.1126/science.1081297. Science. 2003. PMID: 14512626
Computational stabilization of human growth hormone.
Filikov AV, Hayes RJ, Luo P, Stark DM, Chan C, Kundu A, Dahiyat BI. Filikov AV, et al. Among authors: dahiyat bi. Protein Sci. 2002 Jun;11(6):1452-61. doi: 10.1110/ps.3500102. Protein Sci. 2002. PMID: 12021444 Free PMC article.
Engineered antibody Fc variants with enhanced effector function.
Lazar GA, Dang W, Karki S, Vafa O, Peng JS, Hyun L, Chan C, Chung HS, Eivazi A, Yoder SC, Vielmetter J, Carmichael DF, Hayes RJ, Dahiyat BI. Lazar GA, et al. Among authors: dahiyat bi. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4005-10. doi: 10.1073/pnas.0508123103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537476 Free PMC article.
Protein design automation.
Dahiyat BI, Mayo SL. Dahiyat BI, et al. Protein Sci. 1996 May;5(5):895-903. doi: 10.1002/pro.5560050511. Protein Sci. 1996. PMID: 8732761 Free PMC article.
20 results