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Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death.
Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O. Keatinge M, et al. Among authors: da costa m. Hum Mol Genet. 2015 Dec 1;24(23):6640-52. doi: 10.1093/hmg/ddv369. Epub 2015 Sep 16. Hum Mol Genet. 2015. PMID: 26376862 Free PMC article.
Loss of function of parathyroid hormone receptor 1 induces Notch-dependent aortic defects during zebrafish vascular development.
Gray C, Bratt D, Lees J, daCosta M, Plant K, Watson OJ, Solaymani-Kohal S, Tazzyman S, Serbanovic-Canic J, Crossman DC, Keavney BD, Haase A, McMahon K, Gering M, Roehl H, Evans PC, Chico TJ. Gray C, et al. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1257-63. doi: 10.1161/ATVBAHA.112.300590. Epub 2013 Apr 4. Arterioscler Thromb Vasc Biol. 2013. PMID: 23559631
Zebrafish-based small molecule screens for novel cardiovascular drugs.
Novodvorsky P, Da Costa MM, Chico TJ. Novodvorsky P, et al. Among authors: da costa mm. Drug Discov Today Technol. 2013 Spring;10(1):e109-14. doi: 10.1016/j.ddtec.2012.01.005. Drug Discov Today Technol. 2013. PMID: 24050238 Free article. Review.
Essential oil and fenchone extracted from Tetradenia riparia (Hochstetter.) Codd (Lamiaceae) induce oxidative stress in Culex quinquefasciatus larvae (Diptera: Culicidae) without causing lethal effects on non-target animals.
de Oliveira AC, Simões RC, da Silva FMA, Sá ISC, da Costa MLL, Nunomura SM, Nunomura RCS, Roque RA. de Oliveira AC, et al. Among authors: da costa mll. Environ Sci Pollut Res Int. 2024 Apr 26. doi: 10.1007/s11356-024-33440-5. Online ahead of print. Environ Sci Pollut Res Int. 2024. PMID: 38671268
955 results