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Year | Number of Results |
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2019 | 1 |
2020 | 1 |
2022 | 1 |
2023 | 4 |
2024 | 0 |
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7 results
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Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain.
Nat Nanotechnol. 2023 Oct;18(10):1241-1251. doi: 10.1038/s41565-023-01419-x. Epub 2023 Jul 10.
Nat Nanotechnol. 2023.
PMID: 37430038
Free PMC article.
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore BB, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V.
Chen X, et al.
Nat Commun. 2023 Jun 8;14(1):3345. doi: 10.1038/s41467-023-38582-7.
Nat Commun. 2023.
PMID: 37291094
Free PMC article.
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Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors.
Shay TF, Sullivan EE, Ding X, Chen X, Ravindra Kumar S, Goertsen D, Brown D, Crosby A, Vielmetter J, Borsos M, Wolfe DA, Lam AW, Gradinaru V.
Shay TF, et al.
Sci Adv. 2023 Apr 21;9(16):eadg6618. doi: 10.1126/sciadv.adg6618. Epub 2023 Apr 19.
Sci Adv. 2023.
PMID: 37075114
Free PMC article.
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Spatial transcriptomics for profiling the tropism of viral vectors in tissues.
Jang MJ, Coughlin GM, Jackson CR, Chen X, Chuapoco MR, Vendemiatti JL, Wang AZ, Gradinaru V.
Jang MJ, et al.
Nat Biotechnol. 2023 Sep;41(9):1272-1286. doi: 10.1038/s41587-022-01648-w. Epub 2023 Jan 26.
Nat Biotechnol. 2023.
PMID: 36702899
Free PMC article.
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Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems.
Chen X, Ravindra Kumar S, Adams CD, Yang D, Wang T, Wolfe DA, Arokiaraj CM, Ngo V, Campos LJ, Griffiths JA, Ichiki T, Mazmanian SK, Osborne PB, Keast JR, Miller CT, Fox AS, Chiu IM, Gradinaru V.
Chen X, et al.
Neuron. 2022 Jul 20;110(14):2242-2257.e6. doi: 10.1016/j.neuron.2022.05.003. Epub 2022 May 27.
Neuron. 2022.
PMID: 35643078
Free PMC article.
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Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types.
Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V.
Ravindra Kumar S, et al.
Nat Methods. 2020 May;17(5):541-550. doi: 10.1038/s41592-020-0799-7. Epub 2020 Apr 20.
Nat Methods. 2020.
PMID: 32313222
Free PMC article.
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Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics.
Bedbrook CN, Yang KK, Robinson JE, Mackey ED, Gradinaru V, Arnold FH.
Bedbrook CN, et al.
Nat Methods. 2019 Nov;16(11):1176-1184. doi: 10.1038/s41592-019-0583-8. Epub 2019 Oct 14.
Nat Methods. 2019.
PMID: 31611694
Free PMC article.
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