DK62757/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2003	2
2004	1
2005	1
2006	3
2007	1
2008	3
2009	1
2010	2
2011	5
2012	4
2013	1
2024	0

1

Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression.

Tala I, Chen R, Hu T, Fitzpatrick ER, Williams DA, Whitehead IP. Tala I, et al. Leukemia. 2013 Apr;27(5):1080-9. doi: 10.1038/leu.2012.351. Epub 2012 Dec 4. Leukemia. 2013. PMID: 23207522 Free PMC article.

2

Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.

Chang KH, Sanchez-Aguilera A, Shen S, Sengupta A, Madhu MN, Ficker AM, Dunn SK, Kuenzi AM, Arnett JL, Santho RA, Agirre X, Perentesis JP, Deininger MW, Zheng Y, Bustelo XR, Williams DA, Cancelas JA. Chang KH, et al. Blood. 2012 Jul 26;120(4):800-11. doi: 10.1182/blood-2011-06-361709. Epub 2012 Jun 12. Blood. 2012. PMID: 22692505 Free PMC article.

3

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors.

Nieborowska-Skorska M, Kopinski PK, Ray R, Hoser G, Ngaba D, Flis S, Cramer K, Reddy MM, Koptyra M, Penserga T, Glodkowska-Mrowka E, Bolton E, Holyoake TL, Eaves CJ, Cerny-Reiterer S, Valent P, Hochhaus A, Hughes TP, van der Kuip H, Sattler M, Wiktor-Jedrzejczak W, Richardson C, Dorrance A, Stoklosa T, Williams DA, Skorski T. Nieborowska-Skorska M, et al. Blood. 2012 May 3;119(18):4253-63. doi: 10.1182/blood-2011-10-385658. Epub 2012 Mar 12. Blood. 2012. PMID: 22411871 Free PMC article.

4

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.

Lane SW, De Vita S, Alexander KA, Karaman R, Milsom MD, Dorrance AM, Purdon A, Louis L, Bouxsein ML, Williams DA. Lane SW, et al. Blood. 2012 Jan 19;119(3):736-44. doi: 10.1182/blood-2011-07-368753. Epub 2011 Nov 28. Blood. 2012. PMID: 22123845 Free PMC article.

5

Rac deletion in osteoclasts causes severe osteopetrosis.

Croke M, Ross FP, Korhonen M, Williams DA, Zou W, Teitelbaum SL. Croke M, et al. J Cell Sci. 2011 Nov 15;124(Pt 22):3811-21. doi: 10.1242/jcs.086280. Epub 2011 Nov 23. J Cell Sci. 2011. PMID: 22114304 Free PMC article.

6

Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.

Mizukawa B, Wei J, Shrestha M, Wunderlich M, Chou FS, Griesinger A, Harris CE, Kumar AR, Zheng Y, Williams DA, Mulloy JC. Mizukawa B, et al. Blood. 2011 Nov 10;118(19):5235-45. doi: 10.1182/blood-2011-04-351817. Epub 2011 Sep 22. Blood. 2011. PMID: 21940819 Free PMC article.

7

Differential niche and Wnt requirements during acute myeloid leukemia progression.

Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Lane SW, et al. Blood. 2011 Sep 8;118(10):2849-56. doi: 10.1182/blood-2011-03-345165. Epub 2011 Jul 15. Blood. 2011. PMID: 21765021 Free PMC article.

8

Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.

Sanchez-Aguilera A, Lee YJ, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DA. Sanchez-Aguilera A, et al. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9607-12. doi: 10.1073/pnas.1102018108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606370 Free PMC article.

9

Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.

Sengupta A, Arnett J, Dunn S, Williams DA, Cancelas JA. Sengupta A, et al. Blood. 2010 Jul 8;116(1):81-4. doi: 10.1182/blood-2009-10-247437. Epub 2010 Apr 20. Blood. 2010. PMID: 20407032 Free PMC article.

10

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen.

Kalfa TA, Pushkaran S, Zhang X, Johnson JF, Pan D, Daria D, Geiger H, Cancelas JA, Williams DA, Zheng Y. Kalfa TA, et al. Haematologica. 2010 Jan;95(1):27-35. doi: 10.3324/haematol.2009.006239. Haematologica. 2010. PMID: 20065081 Free PMC article.

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