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Human stem cell-based retina on chip as new translational model for validation of AAV retinal gene therapy vectors.
Achberger K, Cipriano M, Düchs MJ, Schön C, Michelfelder S, Stierstorfer B, Lamla T, Kauschke SG, Chuchuy J, Roosz J, Mesch L, Cora V, Pars S, Pashkovskaia N, Corti S, Hartmann SM, Kleger A, Kreuz S, Maier U, Liebau S, Loskill P. Achberger K, et al. Among authors: duchs mj. Stem Cell Reports. 2021 Sep 14;16(9):2242-2256. doi: 10.1016/j.stemcr.2021.08.008. Stem Cell Reports. 2021. PMID: 34525384 Free PMC article.
AAV-mediated expression of a new conformational anti-aggregated α-synuclein antibody prolongs survival in a genetic model of α-synucleinopathies.
Düchs M, Blazevic D, Rechtsteiner P, Kenny C, Lamla T, Low S, Savistchenko J, Neumann M, Melki R, Schönberger T, Stierstorfer B, Wyatt D, Igney F, Ciossek T. Düchs M, et al. NPJ Parkinsons Dis. 2023 Jun 15;9(1):91. doi: 10.1038/s41531-023-00542-9. NPJ Parkinsons Dis. 2023. PMID: 37322068 Free PMC article.
Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice.
Düchs MJ, Kratzer RF, Vieyra-Garcia P, Strobel B, Schönberger T, Groß P, Aljayyoussi G, Gupta A, Lang I, Klein H, Morilla SM, Hopf S, Park J, Kreuz S, Klugmann M, Igney FH. Düchs MJ, et al. Front Immunol. 2024 Mar 15;15:1360063. doi: 10.3389/fimmu.2024.1360063. eCollection 2024. Front Immunol. 2024. PMID: 38558809 Free PMC article.