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DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Strubel A, Münick P, Hartmann O, Chaikuad A, Dreier B, Schaefer JV, Gebel J, Osterburg C, Tuppi M, Schäfer B, Buck V, Rosenfeldt M, Knapp S, Plückthun A, Diefenbacher ME, Dötsch V. Strubel A, et al. Among authors: dotsch v. Cell Death Dis. 2023 Oct 12;14(10):674. doi: 10.1038/s41419-023-06213-0. Cell Death Dis. 2023. PMID: 37828008 Free PMC article.
DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer.
Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V. Deutsch GB, et al. Among authors: dotsch v. Cell. 2011 Feb 18;144(4):566-76. doi: 10.1016/j.cell.2011.01.013. Cell. 2011. PMID: 21335238 Free PMC article.
Analysis of the oligomeric state and transactivation potential of TAp73α.
Luh LM, Kehrloesser S, Deutsch GB, Gebel J, Coutandin D, Schäfer B, Agostini M, Melino G, Dötsch V. Luh LM, et al. Among authors: dotsch v. Cell Death Differ. 2013 Aug;20(8):1008-16. doi: 10.1038/cdd.2013.23. Epub 2013 Mar 29. Cell Death Differ. 2013. PMID: 23538419 Free PMC article.
265 results