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IMI European Lead Factory - democratizing access to high-throughput screening.
Jones PS, Boucharens S, McElroy SP, Morrison A, Honarnejad S, van Boeckel S, van den Hurk H, Basting D, Hüser J, Jaroch S, Ottow E, Benningshof J, Folmer RHA, Leemhuis F, Kramer-Verhulst PM, Nies VJM, Orrling KM, Rijnders T, Pfander C, Engkvist O, Pairaudeau G, Simpson PB, Ortholand JY, Roche D, Dömling A, Kühnert SM, Roevens PWM, van Vlijmen H, van Wanrooij EJA, Verbruggen C, Nussbaumer P, Ovaa H, van der Stelt M, Simonsen KB, Tagmose L, Waldmann H, Duffy J, Finsinger D, Jurzak M, Burgess-Brown NA, Lee WH, Rutjes FPJT, Haag H, Kallus C, Mors H, Dorval T, Lesur B, Ramon Olayo F, Hamza D, Jones G, Pearce C, Piechot A, Tzalis D, Clausen MH, Davis J, Derouane D, Vermeiren C, Kaiser M, Stockman RA, Barrault DV, Pannifer AD, Swedlow JR, Nelson AS, Orru RVA, Ruijter E, van Helden SP, Li VM, Vries T, de Vlieger JSB. Jones PS, et al. Among authors: domling a. Nat Rev Drug Discov. 2022 Apr;21(4):245-246. doi: 10.1038/d41573-021-00196-3. Nat Rev Drug Discov. 2022. PMID: 34907316 No abstract available.
Efficient C2 functionalisation of 2H-2-imidazolines.
Bon RS, Sprenkels NE, Koningstein MM, Schmitz RF, de Kanter FJ, Dömling A, Groen MB, Orru RV. Bon RS, et al. Among authors: domling a. Org Biomol Chem. 2008 Jan 7;6(1):130-7. doi: 10.1039/b713065a. Epub 2007 Nov 8. Org Biomol Chem. 2008. PMID: 18075657
The Catalytic Enantioselective Ugi Four-Component Reactions.
Shaabani S, Dömling A. Shaabani S, et al. Among authors: domling a. Angew Chem Int Ed Engl. 2018 Dec 10;57(50):16266-16268. doi: 10.1002/anie.201811129. Epub 2018 Nov 15. Angew Chem Int Ed Engl. 2018. PMID: 30431219 Free PMC article. Review.
Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines.
Osipyan A, Shaabani S, Warmerdam R, Shishkina SV, Boltz H, Dömling A. Osipyan A, et al. Among authors: domling a. Angew Chem Int Ed Engl. 2020 Jul 20;59(30):12423-12427. doi: 10.1002/anie.202000887. Epub 2020 Mar 2. Angew Chem Int Ed Engl. 2020. PMID: 32048418 Free PMC article.
Rapid approach to complex boronic acids.
Neochoritis CG, Shaabani S, Ahmadianmoghaddam M, Zarganes-Tzitzikas T, Gao L, Novotná M, Mitríková T, Romero AR, Irianti MI, Xu R, Olechno J, Ellson R, Helan V, Kossenjans M, Groves MR, Dömling A. Neochoritis CG, et al. Among authors: domling a. Sci Adv. 2019 Jul 5;5(7):eaaw4607. doi: 10.1126/sciadv.aaw4607. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31281893 Free PMC article.
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions.
Ricardo MG, Ali AM, Plewka J, Surmiak E, Labuzek B, Neochoritis CG, Atmaj J, Skalniak L, Zhang R, Holak TA, Groves M, Rivera DG, Dömling A. Ricardo MG, et al. Among authors: domling a. Angew Chem Int Ed Engl. 2020 Mar 23;59(13):5235-5241. doi: 10.1002/anie.201916257. Epub 2020 Feb 6. Angew Chem Int Ed Engl. 2020. PMID: 31944488
260 results