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PROTACs- a game-changing technology.
Konstantinidou M, Li J, Zhang B, Wang Z, Shaabani S, Ter Brake F, Essa K, Dömling A. Konstantinidou M, et al. Among authors: domling a. Expert Opin Drug Discov. 2019 Dec;14(12):1255-1268. doi: 10.1080/17460441.2019.1659242. Epub 2019 Sep 20. Expert Opin Drug Discov. 2019. PMID: 31538491 Free PMC article. Review.
Inhibitors of programmed cell death 1 (PD-1): a patent review (2010-2015).
Zarganes-Tzitzikas T, Konstantinidou M, Gao Y, Krzemien D, Zak K, Dubin G, Holak TA, Dömling A. Zarganes-Tzitzikas T, et al. Among authors: domling a. Expert Opin Ther Pat. 2016 Sep;26(9):973-7. doi: 10.1080/13543776.2016.1206527. Epub 2016 Jul 6. Expert Opin Ther Pat. 2016. PMID: 27367741 Free PMC article. No abstract available.
Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
Magiera-Mularz K, Skalniak L, Zak KM, Musielak B, Rudzinska-Szostak E, Berlicki Ł, Kocik J, Grudnik P, Sala D, Zarganes-Tzitzikas T, Shaabani S, Dömling A, Dubin G, Holak TA. Magiera-Mularz K, et al. Among authors: domling a. Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13732-13735. doi: 10.1002/anie.201707707. Epub 2017 Sep 26. Angew Chem Int Ed Engl. 2017. PMID: 28881104 Free PMC article.
Concise Synthesis of Tetrazole Macrocycle.
Abdelraheem EMM, de Haan MP, Patil P, Kurpiewska K, Kalinowska-Tłuścik J, Shaabani S, Dömling A. Abdelraheem EMM, et al. Among authors: domling a. Org Lett. 2017 Oct 6;19(19):5078-5081. doi: 10.1021/acs.orglett.7b02319. Epub 2017 Sep 13. Org Lett. 2017. PMID: 28901777 Free PMC article.
Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings.
Abdelraheem EMM, Madhavachary R, Rossetti A, Kurpiewska K, Kalinowska-Tłuścik J, Shaabani S, Dömling A. Abdelraheem EMM, et al. Among authors: domling a. Org Lett. 2017 Nov 17;19(22):6176-6179. doi: 10.1021/acs.orglett.7b03094. Epub 2017 Oct 30. Org Lett. 2017. PMID: 29083197 Free PMC article.
Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies?
Konstantinidou M, Zarganes-Tzitzikas T, Magiera-Mularz K, Holak TA, Dömling A. Konstantinidou M, et al. Among authors: domling a. Angew Chem Int Ed Engl. 2018 Apr 23;57(18):4840-4848. doi: 10.1002/anie.201710407. Epub 2018 Feb 23. Angew Chem Int Ed Engl. 2018. PMID: 29178534 Free PMC article. Review.
Two-Step Macrocycle Synthesis by Classical Ugi Reaction.
Abdelraheem EMM, Khaksar S, Kurpiewska K, Kalinowska-Tłuścik J, Shaabani S, Dömling A. Abdelraheem EMM, et al. Among authors: domling a. J Org Chem. 2018 Feb 2;83(3):1441-1447. doi: 10.1021/acs.joc.7b02984. Epub 2018 Jan 24. J Org Chem. 2018. PMID: 29327924 Free PMC article.
260 results