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Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022.
Díaz-García J, Machado M, Alcalá L, Reigadas E, Pérez-Ayala A, Gómez-García de la Pedrosa E, Gónzalez-Romo F, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J; CANDIMAD study group. Díaz-García J, et al. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0098623. doi: 10.1128/aac.00986-23. Epub 2023 Oct 18. Antimicrob Agents Chemother. 2023. PMID: 38092562 Free PMC article.
Monitoring the Epidemiology and Antifungal Resistance of Yeasts Causing Fungemia in a Tertiary Care Hospital in Madrid, Spain: Any Relevant Changes in the Last 13 Years?
Díaz-García J, Mesquida A, Sánchez-Carrillo C, Reigadas E, Muñoz P, Escribano P, Guinea J. Díaz-García J, et al. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e01827-20. doi: 10.1128/AAC.01827-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33468487 Free PMC article.
Antifungal Susceptibility Testing Identifies the Abdominal Cavity as a Source of Candida glabrata-Resistant Isolates.
Díaz-García J, Mesquida A, Gómez A, Machado M, Martín-Rabadán P, Alcalá L, Sánchez-Carrillo C, Reigadas E, Vicente T, Muñoz P, Escribano P, Guinea J. Díaz-García J, et al. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0124921. doi: 10.1128/AAC.01249-21. Epub 2021 Sep 27. Antimicrob Agents Chemother. 2021. PMID: 34570649 Free PMC article.
Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution.
Díaz-García J, Gómez A, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, Gómez-García de la Pedrosa E, González-Romo F, Merino-Amador P, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Sánchez-Romero I, Durán-Valle MT, Sánchez-García A, Alcoceba E, Muñoz P, Escribano P, Guinea J; CANDIMAD study group. Díaz-García J, et al. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0071022. doi: 10.1128/aac.00710-22. Epub 2022 Jul 19. Antimicrob Agents Chemother. 2022. PMID: 35852369 Free PMC article.
Blood and intra-abdominal Candida spp. from a multicentre study conducted in Madrid using EUCAST: emergence of fluconazole resistance in Candida parapsilosis, low echinocandin resistance and absence of Candida auris.
Díaz-García J, Gómez A, Machado M, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, Gómez-García De La Pedrosa E, González-Romo F, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J; CANDIMAD Study Group. Díaz-García J, et al. J Antimicrob Chemother. 2022 Oct 28;77(11):3102-3109. doi: 10.1093/jac/dkac288. J Antimicrob Chemother. 2022. PMID: 36031723
Candida Genotyping of Blood Culture Isolates from Patients Admitted to 16 Hospitals in Madrid: Genotype Spreading during the COVID-19 Pandemic Driven by Fluconazole-Resistant C. parapsilosis.
Díaz-García J, Gómez A, Machado M, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, de la Pedrosa EG, González-Romo F, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Algarra MM, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J, On Behalf Of The Candimad Study Group. Díaz-García J, et al. J Fungi (Basel). 2022 Nov 21;8(11):1228. doi: 10.3390/jof8111228. J Fungi (Basel). 2022. PMID: 36422050 Free PMC article.
ΔF659 and F659S substitutions at the HS1 of FKS2 gene, along with E655A and W715L upstream and downstream substitutions, correlate with high ibrexafungerp MICs against Candidaglabrata.
Mesquida A, Díaz-García J, Sánchez-Carrillo C, Martín-Rabadán P, Alcalá L, Muñoz P, Escribano P, Guinea J. Mesquida A, et al. Clin Microbiol Infect. 2022 Aug;28(8):1154.e5-1154.e8. doi: 10.1016/j.cmi.2022.04.003. Epub 2022 Apr 12. Clin Microbiol Infect. 2022. PMID: 35427779 Free article.
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