Díaz JF - Search Results

1

Total Synthesis of Amphidinolide K, a Macrolide That Stabilizes F-Actin.

Sánchez D, Andreou T, Costa AM, Meyer KG, Williams DR, Barasoain I, Díaz JF, Lucena-Agell D, Vilarrasa J. Sánchez D, et al. Among authors: diaz jf. J Org Chem. 2015 Sep 4;80(17):8511-9. doi: 10.1021/acs.joc.5b00966. Epub 2015 Jun 23. J Org Chem. 2015. PMID: 26079383

2

Fast kinetics of Taxol binding to microtubules. Effects of solution variables and microtubule-associated proteins.

Díaz JF, Barasoain I, Andreu JM. Díaz JF, et al. J Biol Chem. 2003 Mar 7;278(10):8407-19. doi: 10.1074/jbc.M211163200. Epub 2002 Dec 20. J Biol Chem. 2003. PMID: 12496245 Free article.

3

Macromolecular accessibility of fluorescent taxoids bound at a paclitaxel binding site in the microtubule surface.

Díaz JF, Barasoain I, Souto AA, Amat-Guerri F, Andreu JM. Díaz JF, et al. J Biol Chem. 2005 Feb 4;280(5):3928-37. doi: 10.1074/jbc.M407816200. Epub 2004 Nov 18. J Biol Chem. 2005. PMID: 15550392 Free article.

4

Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain.

Paterson I, Menche D, Håkansson AE, Longstaff A, Wong D, Barasoain I, Buey RM, Díaz JF. Paterson I, et al. Among authors: diaz jf. Bioorg Med Chem Lett. 2005 May 2;15(9):2243-7. doi: 10.1016/j.bmcl.2005.03.018. Bioorg Med Chem Lett. 2005. PMID: 15837302

5

Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity.

Buey RM, Barasoain I, Jackson E, Meyer A, Giannakakou P, Paterson I, Mooberry S, Andreu JM, Díaz JF. Buey RM, et al. Among authors: diaz jf. Chem Biol. 2005 Dec;12(12):1269-79. doi: 10.1016/j.chembiol.2005.09.010. Chem Biol. 2005. PMID: 16356844

6

Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.

Buey RM, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal CD, Day BW, Sorensen EJ, López JA, Andreu JM, Hamel E, Díaz JF. Buey RM, et al. Among authors: diaz jf. Nat Chem Biol. 2007 Feb;3(2):117-25. doi: 10.1038/nchembio853. Epub 2007 Jan 7. Nat Chem Biol. 2007. PMID: 17206139 Free article.

7

Synthesis, biological evaluations, and tubulin binding poses of C-2alpha sulfur linked taxol analogues.

Wang L, Alcaraz AA, Matesanz R, Yang CG, Barasoain I, Díaz JF, Li YZ, Snyder JP, Fang WS. Wang L, et al. Among authors: diaz jf. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3191-4. doi: 10.1016/j.bmcl.2007.03.026. Epub 2007 Mar 14. Bioorg Med Chem Lett. 2007. PMID: 17395465

8

The total synthesis and biological properties of the cytotoxic macrolide FD-891 and its non-natural (Z)-C12 isomer.

García-Fortanet J, Murga J, Carda M, Marco JA, Matesanz R, Díaz JF, Barasoain I. García-Fortanet J, et al. Among authors: diaz jf. Chemistry. 2007;13(18):5060-74. doi: 10.1002/chem.200700342. Chemistry. 2007. PMID: 17516610

9

Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.

Matesanz R, Barasoain I, Yang CG, Wang L, Li X, de Inés C, Coderch C, Gago F, Barbero JJ, Andreu JM, Fang WS, Díaz JF. Matesanz R, et al. Among authors: diaz jf. Chem Biol. 2008 Jun;15(6):573-85. doi: 10.1016/j.chembiol.2008.05.008. Chem Biol. 2008. PMID: 18559268

10

Synthesis and biological activities of high affinity taxane-based fluorescent probes.

Li X, Barasoain I, Matesanz R, Díaz JF, Fang WS. Li X, et al. Among authors: diaz jf. Bioorg Med Chem Lett. 2009 Feb 1;19(3):751-4. doi: 10.1016/j.bmcl.2008.12.018. Epub 2008 Dec 10. Bioorg Med Chem Lett. 2009. PMID: 19128972

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