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Titanium dioxide nanoparticles induce an adaptive inflammatory response and invasion and proliferation of lung epithelial cells in chorioallantoic membrane.
Medina-Reyes EI, Déciga-Alcaraz A, Freyre-Fonseca V, Delgado-Buenrostro NL, Flores-Flores JO, Gutiérrez-López GF, Sánchez-Pérez Y, García-Cuéllar CM, Pedraza-Chaverri J, Chirino YI. Medina-Reyes EI, et al. Environ Res. 2015 Jan;136:424-34. doi: 10.1016/j.envres.2014.10.016. Epub 2014 Nov 25. Environ Res. 2015. PMID: 25460664
Food-grade titanium dioxide (E171) by solid or liquid matrix administration induces inflammation, germ cells sloughing in seminiferous tubules and blood-testis barrier disruption in mice.
Rodríguez-Escamilla JC, Medina-Reyes EI, Rodríguez-Ibarra C, Déciga-Alcaraz A, Flores-Flores JO, Ganem-Rondero A, Rodríguez-Sosa M, Terrazas LI, Delgado-Buenrostro NL, Chirino YI. Rodríguez-Escamilla JC, et al. J Appl Toxicol. 2019 Nov;39(11):1586-1605. doi: 10.1002/jat.3842. Epub 2019 Aug 15. J Appl Toxicol. 2019. PMID: 31415109
Differences in cytotoxicity of lung epithelial cells exposed to titanium dioxide nanofibers and nanoparticles: Comparison of air-liquid interface and submerged cell cultures.
Medina-Reyes EI, Delgado-Buenrostro NL, Leseman DL, Déciga-Alcaraz A, He R, Gremmer ER, Fokkens PHB, Flores-Flores JO, Cassee FR, Chirino YI. Medina-Reyes EI, et al. Toxicol In Vitro. 2020 Jun;65:104798. doi: 10.1016/j.tiv.2020.104798. Epub 2020 Feb 19. Toxicol In Vitro. 2020. PMID: 32084520
Irreversible disruption of the cytoskeleton as induced by non-cytotoxic exposure to titanium dioxide nanoparticles in lung epithelial cells.
Déciga-Alcaraz A, Delgado-Buenrostro NL, Ispanixtlahuatl-Meráz O, Freyre-Fonseca V, Flores-Flores JO, Ganem-Rondero A, Vaca-Paniagua F, Pilar Ramos-Godinez MD, Morales-Barcenas R, Sánchez-Pérez Y, García-Cuéllar CM, Chirino YI. Déciga-Alcaraz A, et al. Chem Biol Interact. 2020 May 25;323:109063. doi: 10.1016/j.cbi.2020.109063. Epub 2020 Mar 26. Chem Biol Interact. 2020. PMID: 32224134
Toxicity of engineered nanomaterials with different physicochemical properties and the role of protein corona on cellular uptake and intrinsic ROS production.
Déciga-Alcaraz A, Medina-Reyes EI, Delgado-Buenrostro NL, Rodríguez-Ibarra C, Ganem-Rondero A, Vázquez-Zapién GJ, Mata-Miranda MM, Limón-Pacheco JH, García-Cuéllar CM, Sánchez-Pérez Y, Chirino YI. Déciga-Alcaraz A, et al. Toxicology. 2020 Sep;442:152545. doi: 10.1016/j.tox.2020.152545. Epub 2020 Aug 2. Toxicology. 2020. PMID: 32755642
Food-grade titanium dioxide (E171) induces anxiety, adenomas in colon and goblet cells hyperplasia in a regular diet model and microvesicular steatosis in a high fat diet model.
Medina-Reyes EI, Delgado-Buenrostro NL, Díaz-Urbina D, Rodríguez-Ibarra C, Déciga-Alcaraz A, González MI, Reyes JL, Villamar-Duque TE, Flores-Sánchez ML, Hernández-Pando R, Mancilla-Díaz JM, Chirino YI, Pedraza-Chaverri J. Medina-Reyes EI, et al. Among authors: deciga alcaraz a. Food Chem Toxicol. 2020 Dec;146:111786. doi: 10.1016/j.fct.2020.111786. Epub 2020 Oct 8. Food Chem Toxicol. 2020. PMID: 33038453
15 results