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Inhibition of aldose-reductase-2 by a benzofuroxane derivative bf-5m increases the expression of kcne1, kcnq1 in high glucose cultured H9c2 cardiac cells and sudden cardiac death.
Trotta MC, Salerno M, Brigida AL, Monda V, Messina A, Fiore C, Avola R, Bernardini R, Sessa F, Marsala G, Zanghì GN, Messina G, D'Amico M, Di Filippo C. Trotta MC, et al. Oncotarget. 2017 Dec 14;9(25):17257-17269. doi: 10.18632/oncotarget.23270. eCollection 2018 Apr 3. Oncotarget. 2017. PMID: 29707106 Free PMC article.
The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome.
Trotta MC, Maisto R, Guida F, Boccella S, Luongo L, Balta C, D'Amico G, Herman H, Hermenean A, Bucolo C, D'Amico M. Trotta MC, et al. PLoS One. 2019 Jan 18;14(1):e0211005. doi: 10.1371/journal.pone.0211005. eCollection 2019. PLoS One. 2019. PMID: 30657794 Free PMC article.
741 results