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MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans.
Esposito I, Cicconi P, D'Alise AM, Brown A, Esposito M, Swadling L, Holst PJ, Bassi MR, Stornaiuolo M, Mori F, Vassilev V, Li W, Donnison T, Gentile C, Turner B, von Delft A, Del Sorbo M, Barra F, Contino AM, Abbate A, Novellino E, Thomsen AR, Christensen JP, Lahm A, Grazioli F, Ammendola V, Siani L, Colloca S, Klenerman P, Nicosia A, Dorrell L, Folgori A, Capone S, Barnes E; PEACHI Consortium. Esposito I, et al. Sci Transl Med. 2020 Jun 17;12(548):eaaz7715. doi: 10.1126/scitranslmed.aaz7715. Sci Transl Med. 2020. PMID: 32554708 Free PMC article.
Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates.
Capone S, Naddeo M, D'Alise AM, Abbate A, Grazioli F, Del Gaudio A, Del Sorbo M, Esposito ML, Ammendola V, Perretta G, Taglioni A, Colloca S, Nicosia A, Cortese R, Folgori A. Capone S, et al. Mol Ther. 2014 May;22(5):1039-47. doi: 10.1038/mt.2014.15. Epub 2014 Jan 30. Mol Ther. 2014. PMID: 24476798 Free PMC article.
Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates.
Pierantoni A, Esposito ML, Ammendola V, Napolitano F, Grazioli F, Abbate A, Del Sorbo M, Siani L, D'Alise AM, Taglioni A, Perretta G, Siccardi A, Soprana E, Panigada M, Thom M, Scarselli E, Folgori A, Colloca S, Taylor G, Cortese R, Nicosia A, Capone S, Vitelli A. Pierantoni A, et al. Mol Ther Methods Clin Dev. 2015 May 20;2:15018. doi: 10.1038/mtm.2015.18. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26015988 Free PMC article.
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade.
D'Alise AM, Leoni G, Cotugno G, Troise F, Langone F, Fichera I, De Lucia M, Avalle L, Vitale R, Leuzzi A, Bignone V, Di Matteo E, Tucci FG, Poli V, Lahm A, Catanese MT, Folgori A, Colloca S, Nicosia A, Scarselli E. D'Alise AM, et al. Nat Commun. 2019 Jun 19;10(1):2688. doi: 10.1038/s41467-019-10594-2. Nat Commun. 2019. PMID: 31217437 Free PMC article.
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
Leoni G, D'Alise AM, Cotugno G, Langone F, Garzia I, De Lucia M, Fichera I, Vitale R, Bignone V, Tucci FG, Mori F, Leuzzi A, Di Matteo E, Troise F, Abbate A, Merone R, Ruzza V, Diodoro MG, Yadav M, Gordon-Alonso M, Vanhaver C, Panigada M, Soprana E, Siccardi A, Folgori A, Colloca S, van der Bruggen P, Nicosia A, Lahm A, Catanese MT, Scarselli E. Leoni G, et al. Cancer Res. 2020 Sep 15;80(18):3972-3982. doi: 10.1158/0008-5472.CAN-20-1072. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690723
Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment.
De Lucia M, Cotugno G, Bignone V, Garzia I, Nocchi L, Langone F, Petrovic B, Sasso E, Pepe S, Froechlich G, Gentile C, Zambrano N, Campadelli-Fiume G, Nicosia A, Scarselli E, D'Alise AM. De Lucia M, et al. Mol Ther Oncolytics. 2020 Oct 14;19:253-264. doi: 10.1016/j.omto.2020.10.006. eCollection 2020 Dec 16. Mol Ther Oncolytics. 2020. PMID: 33209980 Free PMC article.
35 results