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Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis.
Freitas A, Alves-Filho JC, Trevelin SC, Spiller F, Suavinha MM, Nascimento DC, Pestana CR, Dal-Secco D, Sônego F, Czaikoski PG, Curti C, Barja-Fidalgo C, Cunha FQ. Freitas A, et al. Among authors: czaikoski pg. Shock. 2011 Jun;35(6):550-9. doi: 10.1097/SHK.0b013e31820e1ef0. Shock. 2011. PMID: 21330952
Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis.
Czaikoski PG, Nascimento DC, Sônego F, de Freitas A, Turato WM, de Carvalho MA, Santos RS, de Oliveira GP, dos Santos Samary C, Tefe-Silva C, Alves-Filho JC, Ferreira SH, Rossi MA, Rocco PR, Spiller F, Cunha FQ. Czaikoski PG, et al. Shock. 2013 Apr;39(4):389-96. doi: 10.1097/SHK.0b013e31828bbcf9. Shock. 2013. PMID: 23481491
CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis.
Castanheira FVES, de Lima KA, Cebinelli GCM, Sônego F, Kanashiro A, Colon DF, Borges V, Czaikoski PG, Mota JM, Cunha TM, Alves-Filho JC, Liew FY, Cunha FQ. Castanheira FVES, et al. Among authors: czaikoski pg. Shock. 2019 Nov;52(5):e100-e106. doi: 10.1097/SHK.0000000000001301. Shock. 2019. PMID: 30724784
Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP channel activation.
Spiller F, Orrico MI, Nascimento DC, Czaikoski PG, Souto FO, Alves-Filho JC, Freitas A, Carlos D, Montenegro MF, Neto AF, Ferreira SH, Rossi MA, Hothersall JS, Assreuy J, Cunha FQ. Spiller F, et al. Among authors: czaikoski pg. Am J Respir Crit Care Med. 2010 Aug 1;182(3):360-8. doi: 10.1164/rccm.200907-1145OC. Epub 2010 Mar 25. Am J Respir Crit Care Med. 2010. PMID: 20339148
Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis.
Czaikoski PG, Mota JM, Nascimento DC, Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL, Barroso-Sousa R, Souto FO, Pazin-Filho A, Figueiredo F, Alves-Filho JC, Cunha FQ. Czaikoski PG, et al. PLoS One. 2016 Feb 5;11(2):e0148142. doi: 10.1371/journal.pone.0148142. eCollection 2016. PLoS One. 2016. PMID: 26849138 Free PMC article.
MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response.
Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ. Sônego F, et al. Among authors: czaikoski pg. PLoS One. 2014 Aug 1;9(8):e103734. doi: 10.1371/journal.pone.0103734. eCollection 2014. PLoS One. 2014. PMID: 25084278 Free PMC article.
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