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The IRG1-itaconate axis protects from cholesterol-induced inflammation and atherosclerosis.
Cyr Y, Bozal FK, Barcia Durán JG, Newman AAC, Amadori L, Smyrnis P, Gourvest M, Das D, Gildea M, Kaur R, Zhang T, Wang KM, Von Itter R, Schlegel PM, Dupuis SD, Sanchez BF, Schmidt AM, Fisher EA, van Solingen C, Giannarelli C, Moore KJ. Cyr Y, et al. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2400675121. doi: 10.1073/pnas.2400675121. Epub 2024 Apr 2. Proc Natl Acad Sci U S A. 2024. PMID: 38564634 Free PMC article.
Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis.
Amadori L, Calcagno C, Fernandez DM, Koplev S, Fernandez N, Kaur R, Mury P, Khan NS, Sajja S, Shamailova R, Cyr Y, Jeon M, Hill CA, Chong PS, Naidu S, Sakurai K, Ghotbi AA, Soler R, Eberhardt N, Rahman A, Faries P, Moore KJ, Fayad ZA, Ma'ayan A, Giannarelli C. Amadori L, et al. Among authors: cyr y. Nat Cardiovasc Res. 2023 Jun;2(6):550-571. doi: 10.1038/s44161-023-00278-y. Epub 2023 Jun 8. Nat Cardiovasc Res. 2023. PMID: 37771373 Free PMC article.
Erratum: Publisher Correction: Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis.
Amadori L, Calcagno C, Fernandez DM, Koplev S, Fernandez N, Kaur R, Mury P, Khan NS, Sajja S, Shamailova R, Cyr Y, Jeon M, Hill CA, Chong PS, Naidu S, Sakurai K, Ghotbi AA, Soler R, Eberhardt N, Rahman A, Faries P, Moore KJ, Fayad ZA, Ma'ayan A, Giannarelli C. Amadori L, et al. Among authors: cyr y. Nat Cardiovasc Res. 2023;2(8):793. doi: 10.1038/s44161-023-00310-1. Epub 2023 Jul 4. Nat Cardiovasc Res. 2023. PMID: 38666036 Free PMC article.
Long noncoding RNA CHROMR regulates antiviral immunity in humans.
van Solingen C, Cyr Y, Scacalossi KR, de Vries M, Barrett TJ, de Jong A, Gourvest M, Zhang T, Peled D, Kher R, Cornwell M, Gildea MA, Brown EJ, Fanucchi S, Mhlanga MM, Berger JS, Dittmann M, Moore KJ. van Solingen C, et al. Among authors: cyr y. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2210321119. doi: 10.1073/pnas.2210321119. Epub 2022 Aug 24. Proc Natl Acad Sci U S A. 2022. PMID: 36001732 Free PMC article.
Advancing therapeutic targeting of the vulnerable plaque.
Newman AAC, Cyr Y, Moore KJ. Newman AAC, et al. Among authors: cyr y. Eur Heart J. 2022 May 14;43(19):1878-1880. doi: 10.1093/eurheartj/ehac060. Eur Heart J. 2022. PMID: 35567566 No abstract available.
Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.
Schlegel M, Sharma M, Brown EJ, Newman AAC, Cyr Y, Afonso MS, Corr EM, Koelwyn GJ, van Solingen C, Guzman J, Farhat R, Nikain CA, Shanley LC, Peled D, Schmidt AM, Fisher EA, Moore KJ. Schlegel M, et al. Among authors: cyr y. Circ Res. 2021 Aug 20;129(5):530-546. doi: 10.1161/CIRCRESAHA.121.319313. Epub 2021 Jul 22. Circ Res. 2021. PMID: 34289717 Free PMC article.
MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging.
Afonso MS, Verma N, van Solingen C, Cyr Y, Sharma M, Perie L, Corr EM, Schlegel M, Shanley LC, Peled D, Yoo JY, Schmidt AM, Mueller E, Moore KJ. Afonso MS, et al. Among authors: cyr y. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1360-1373. doi: 10.1161/ATVBAHA.120.315798. Epub 2021 Mar 4. Arterioscler Thromb Vasc Biol. 2021. PMID: 33657886 Free PMC article.
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