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The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.
Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. Lynes MD, et al. Among authors: cypess am. Nat Med. 2017 May;23(5):631-637. doi: 10.1038/nm.4297. Epub 2017 Mar 27. Nat Med. 2017. PMID: 28346411 Free PMC article.
Identification and importance of brown adipose tissue in adult humans.
Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, Kuo FC, Palmer EL, Tseng YH, Doria A, Kolodny GM, Kahn CR. Cypess AM, et al. N Engl J Med. 2009 Apr 9;360(15):1509-17. doi: 10.1056/NEJMoa0810780. N Engl J Med. 2009. PMID: 19357406 Free PMC article.
Brown fat as a therapy for obesity and diabetes.
Cypess AM, Kahn CR. Cypess AM, et al. Curr Opin Endocrinol Diabetes Obes. 2010 Apr;17(2):143-9. doi: 10.1097/MED.0b013e328337a81f. Curr Opin Endocrinol Diabetes Obes. 2010. PMID: 20160646 Free PMC article. Review.
Cellular bioenergetics as a target for obesity therapy.
Tseng YH, Cypess AM, Kahn CR. Tseng YH, et al. Among authors: cypess am. Nat Rev Drug Discov. 2010 Jun;9(6):465-82. doi: 10.1038/nrd3138. Nat Rev Drug Discov. 2010. PMID: 20514071 Free PMC article. Review.
Cold but not sympathomimetics activates human brown adipose tissue in vivo.
Cypess AM, Chen YC, Sze C, Wang K, English J, Chan O, Holman AR, Tal I, Palmer MR, Kolodny GM, Kahn CR. Cypess AM, et al. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10001-5. doi: 10.1073/pnas.1207911109. Epub 2012 Jun 4. Proc Natl Acad Sci U S A. 2012. PMID: 22665804 Free PMC article.
Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.
Cypess AM, White AP, Vernochet C, Schulz TJ, Xue R, Sass CA, Huang TL, Roberts-Toler C, Weiner LS, Sze C, Chacko AT, Deschamps LN, Herder LM, Truchan N, Glasgow AL, Holman AR, Gavrila A, Hasselgren PO, Mori MA, Molla M, Tseng YH. Cypess AM, et al. Nat Med. 2013 May;19(5):635-9. doi: 10.1038/nm.3112. Epub 2013 Apr 21. Nat Med. 2013. PMID: 23603815 Free PMC article.
91 results