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Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells.
Mol Cell. 2021 Oct 7;81(19):4026-4040.e8. doi: 10.1016/j.molcel.2021.09.013.
Mol Cell. 2021.
PMID: 34624216
Free PMC article.
PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells.
Quinet A, Tirman S, Jackson J, Šviković S, Lemaçon D, Carvajal-Maldonado D, González-Acosta D, Vessoni AT, Cybulla E, Wood M, Tavis S, Batista LFZ, Méndez J, Sale JE, Vindigni A.
Quinet A, et al. Among authors: cybulla e.
Mol Cell. 2020 Feb 6;77(3):461-474.e9. doi: 10.1016/j.molcel.2019.10.008. Epub 2019 Oct 29.
Mol Cell. 2020.
PMID: 31676232
Free PMC article.
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PRIMPOL ready, set, reprime!
Tirman S, Cybulla E, Quinet A, Meroni A, Vindigni A.
Tirman S, et al. Among authors: cybulla e.
Crit Rev Biochem Mol Biol. 2021 Feb;56(1):17-30. doi: 10.1080/10409238.2020.1841089. Epub 2020 Nov 12.
Crit Rev Biochem Mol Biol. 2021.
PMID: 33179522
Free PMC article.
Review.
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To skip or not to skip: choosing repriming to tolerate DNA damage.
Quinet A, Tirman S, Cybulla E, Meroni A, Vindigni A.
Quinet A, et al. Among authors: cybulla e.
Mol Cell. 2021 Feb 18;81(4):649-658. doi: 10.1016/j.molcel.2021.01.012. Epub 2021 Jan 29.
Mol Cell. 2021.
PMID: 33515486
Free PMC article.
Review.
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A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin.
Kreienkamp R, Graziano S, Coll-Bonfill N, Bedia-Diaz G, Cybulla E, Vindigni A, Dorsett D, Kubben N, Batista LFZ, Gonzalo S.
Kreienkamp R, et al. Among authors: cybulla e.
Cell Rep. 2018 Feb 20;22(8):2006-2015. doi: 10.1016/j.celrep.2018.01.090.
Cell Rep. 2018.
PMID: 29466729
Free PMC article.
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Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer.
Gupta VG, Hirst J, Petersen S, Roby KF, Kusch M, Zhou H, Clive ML, Jewell A, Pathak HB, Godwin AK, Wilson AJ, Crispens MA, Cybulla E, Vindigni A, Fuh KC, Khabele D.
Gupta VG, et al. Among authors: cybulla e.
Gynecol Oncol. 2021 Jul;162(1):163-172. doi: 10.1016/j.ygyno.2021.04.015. Epub 2021 Apr 16.
Gynecol Oncol. 2021.
PMID: 33867143
Free PMC article.
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GAS6/AXL Inhibition Enhances Ovarian Cancer Sensitivity to Chemotherapy and PARP Inhibition through Increased DNA Damage and Enhanced Replication Stress.
Mullen MM, Lomonosova E, Toboni MD, Oplt A, Cybulla E, Blachut B, Zhao P, Noia H, Wilke D, Rankin EB, Kuroki LM, Hagemann AR, Hagemann IS, McCourt CK, Thaker PH, Mutch DG, Powell MA, Mosammaparast N, Vindigni A, Fuh KC.
Mullen MM, et al. Among authors: cybulla e.
Mol Cancer Res. 2022 Feb;20(2):265-279. doi: 10.1158/1541-7786.MCR-21-0302. Epub 2021 Oct 20.
Mol Cancer Res. 2022.
PMID: 34670865
Free PMC article.
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Leveraging the replication stress response to optimize cancer therapy.
Cybulla E, Vindigni A.
Cybulla E, et al.
Nat Rev Cancer. 2023 Jan;23(1):6-24. doi: 10.1038/s41568-022-00518-6. Epub 2022 Nov 2.
Nat Rev Cancer. 2023.
PMID: 36323800
Free PMC article.
Review.
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