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The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2).
da Costa V, van Vliet SJ, Carasi P, Frigerio S, García PA, Croci DO, Festari MF, Costa M, Landeira M, Rodríguez-Zraquia SA, Cagnoni AJ, Cutine AM, Rabinovich GA, Osinaga E, Mariño KV, Freire T. da Costa V, et al. Among authors: cutine am. Cancer Lett. 2021 Oct 10;518:72-81. doi: 10.1016/j.canlet.2021.06.012. Epub 2021 Jun 16. Cancer Lett. 2021. PMID: 34144098
Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits.
Morosi LG, Cutine AM, Cagnoni AJ, Manselle-Cocco MN, Croci DO, Merlo JP, Morales RM, May M, Pérez-Sáez JM, Girotti MR, Méndez-Huergo SP, Pucci B, Gil AH, Huernos SP, Docena GH, Sambuelli AM, Toscano MA, Rabinovich GA, Mariño KV. Morosi LG, et al. Among authors: cutine am. Sci Adv. 2021 Jun 18;7(25):eabf8630. doi: 10.1126/sciadv.abf8630. Print 2021 Jun. Sci Adv. 2021. PMID: 34144987 Free PMC article.