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Page 1
Identification of human brain tumour initiating cells.
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. Singh SK, et al. Among authors: cusimano md. Nature. 2004 Nov 18;432(7015):396-401. doi: 10.1038/nature03128. Nature. 2004. PMID: 15549107 Free article.
MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.
Gallo M, Coutinho FJ, Vanner RJ, Gayden T, Mack SC, Murison A, Remke M, Li R, Takayama N, Desai K, Lee L, Lan X, Park NI, Barsyte-Lovejoy D, Smil D, Sturm D, Kushida MM, Head R, Cusimano MD, Bernstein M, Clarke ID, Dick JE, Pfister SM, Rich JN, Arrowsmith CH, Taylor MD, Jabado N, Bazett-Jones DP, Lupien M, Dirks PB. Gallo M, et al. Among authors: cusimano md. Cancer Cell. 2015 Dec 14;28(6):715-729. doi: 10.1016/j.ccell.2015.10.005. Epub 2015 Nov 25. Cancer Cell. 2015. PMID: 26626085 Free article.
ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.
Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB. Park NI, et al. Among authors: cusimano md. Cell Stem Cell. 2017 Aug 3;21(2):209-224.e7. doi: 10.1016/j.stem.2017.06.004. Epub 2017 Jul 14. Cell Stem Cell. 2017. PMID: 28712938 Free article.
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.
Lan X, Jörg DJ, Cavalli FMG, Richards LM, Nguyen LV, Vanner RJ, Guilhamon P, Lee L, Kushida MM, Pellacani D, Park NI, Coutinho FJ, Whetstone H, Selvadurai HJ, Che C, Luu B, Carles A, Moksa M, Rastegar N, Head R, Dolma S, Prinos P, Cusimano MD, Das S, Bernstein M, Arrowsmith CH, Mungall AJ, Moore RA, Ma Y, Gallo M, Lupien M, Pugh TJ, Taylor MD, Hirst M, Eaves CJ, Simons BD, Dirks PB. Lan X, et al. Among authors: cusimano md. Nature. 2017 Sep 14;549(7671):227-232. doi: 10.1038/nature23666. Epub 2017 Aug 30. Nature. 2017. PMID: 28854171 Free PMC article.
Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.
Rajakulendran N, Rowland KJ, Selvadurai HJ, Ahmadi M, Park NI, Naumenko S, Dolma S, Ward RJ, So M, Lee L, MacLeod G, Pasiliao C, Brandon C, Clarke ID, Cusimano MD, Bernstein M, Batada N, Angers S, Dirks PB. Rajakulendran N, et al. Among authors: cusimano md. Genes Dev. 2019 May 1;33(9-10):498-510. doi: 10.1101/gad.321968.118. Epub 2019 Mar 6. Genes Dev. 2019. PMID: 30842215 Free PMC article.
PRMT5 inhibition disrupts splicing and stemness in glioblastoma.
Sachamitr P, Ho JC, Ciamponi FE, Ba-Alawi W, Coutinho FJ, Guilhamon P, Kushida MM, Cavalli FMG, Lee L, Rastegar N, Vu V, Sánchez-Osuna M, Coulombe-Huntington J, Kanshin E, Whetstone H, Durand M, Thibault P, Hart K, Mangos M, Veyhl J, Chen W, Tran N, Duong BC, Aman AM, Che X, Lan X, Whitley O, Zaslaver O, Barsyte-Lovejoy D, Richards LM, Restall I, Caudy A, Röst HL, Bonday ZQ, Bernstein M, Das S, Cusimano MD, Spears J, Bader GD, Pugh TJ, Tyers M, Lupien M, Haibe-Kains B, Artee Luchman H, Weiss S, Massirer KB, Prinos P, Arrowsmith CH, Dirks PB. Sachamitr P, et al. Among authors: cusimano md. Nat Commun. 2021 Feb 12;12(1):979. doi: 10.1038/s41467-021-21204-5. Nat Commun. 2021. PMID: 33579912 Free PMC article.
Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.
Richards LM, Whitley OKN, MacLeod G, Cavalli FMG, Coutinho FJ, Jaramillo JE, Svergun N, Riverin M, Croucher DC, Kushida M, Yu K, Guilhamon P, Rastegar N, Ahmadi M, Bhatti JK, Bozek DA, Li N, Lee L, Che C, Luis E, Park NI, Xu Z, Ketela T, Moore RA, Marra MA, Spears J, Cusimano MD, Das S, Bernstein M, Haibe-Kains B, Lupien M, Luchman HA, Weiss S, Angers S, Dirks PB, Bader GD, Pugh TJ. Richards LM, et al. Among authors: cusimano md. Nat Cancer. 2021 Feb;2(2):157-173. doi: 10.1038/s43018-020-00154-9. Epub 2021 Jan 4. Nat Cancer. 2021. PMID: 35122077
Pediatric multicompartmental trigeminal schwannoma: illustrative case.
Landry AP, Ye VC, Vaughan KA, Drake JM, Dirks PB, Cusimano MD. Landry AP, et al. Among authors: cusimano md. J Neurosurg Case Lessons. 2021 May 17;1(20):CASE2171. doi: 10.3171/CASE2171. eCollection 2021 May 17. J Neurosurg Case Lessons. 2021. PMID: 35855022 Free PMC article.
Imaging of murine brain tumors using a 1.5 Tesla clinical MRI system.
van Furth WR, Laughlin S, Taylor MD, Salhia B, Mainprize T, Henkelman M, Cusimano MD, Ackerley C, Rutka JT. van Furth WR, et al. Among authors: cusimano md. Can J Neurol Sci. 2003 Nov;30(4):326-32. doi: 10.1017/s0317167100003036. Can J Neurol Sci. 2003. PMID: 14672264
ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.
Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB. Park NI, et al. Among authors: cusimano md. Cell Stem Cell. 2017 Sep 7;21(3):411. doi: 10.1016/j.stem.2017.08.008. Cell Stem Cell. 2017. PMID: 28886368 Free article. No abstract available.
381 results