Curran T - Search Results

1

Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.

Liu Y, Yuelling LW, Wang Y, Du F, Gordon RE, O'Brien JA, Ng JMY, Robins S, Lee EH, Liu H, Curran T, Yang ZJ. Liu Y, et al. Among authors: curran t. Cancer Res. 2017 Dec 1;77(23):6692-6703. doi: 10.1158/0008-5472.CAN-17-1463. Epub 2017 Oct 6. Cancer Res. 2017. PMID: 28986380 Free PMC article.

2

The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched.

Wetmore C, Eberhart DE, Curran T. Wetmore C, et al. Among authors: curran t. Cancer Res. 2000 Apr 15;60(8):2239-46. Cancer Res. 2000. PMID: 10786690

3

Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.

Wetmore C, Eberhart DE, Curran T. Wetmore C, et al. Among authors: curran t. Cancer Res. 2001 Jan 15;61(2):513-6. Cancer Res. 2001. PMID: 11212243

4

A molecular fingerprint for medulloblastoma.

Lee Y, Miller HL, Jensen P, Hernan R, Connelly M, Wetmore C, Zindy F, Roussel MF, Curran T, Gilbertson RJ, McKinnon PJ. Lee Y, et al. Among authors: curran t. Cancer Res. 2003 Sep 1;63(17):5428-37. Cancer Res. 2003. PMID: 14500378

5

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

Romer JT, Kimura H, Magdaleno S, Sasai K, Fuller C, Baines H, Connelly M, Stewart CF, Gould S, Rubin LL, Curran T. Romer JT, et al. Among authors: curran t. Cancer Cell. 2004 Sep;6(3):229-40. doi: 10.1016/j.ccr.2004.08.019. Cancer Cell. 2004. PMID: 15380514 Free article.

6

Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics.

Romer J, Curran T. Romer J, et al. Among authors: curran t. Cancer Res. 2005 Jun 15;65(12):4975-8. doi: 10.1158/0008-5472.CAN-05-0481. Cancer Res. 2005. PMID: 15958535 Review.

7

Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies.

Sasai K, Romer JT, Lee Y, Finkelstein D, Fuller C, McKinnon PJ, Curran T. Sasai K, et al. Among authors: curran t. Cancer Res. 2006 Apr 15;66(8):4215-22. doi: 10.1158/0008-5472.CAN-05-4505. Cancer Res. 2006. PMID: 16618744

8

Patched2 modulates tumorigenesis in patched1 heterozygous mice.

Lee Y, Miller HL, Russell HR, Boyd K, Curran T, McKinnon PJ. Lee Y, et al. Among authors: curran t. Cancer Res. 2006 Jul 15;66(14):6964-71. doi: 10.1158/0008-5472.CAN-06-0505. Cancer Res. 2006. PMID: 16849540

9

Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor.

Sasai K, Romer JT, Kimura H, Eberhart DE, Rice DS, Curran T. Sasai K, et al. Among authors: curran t. Cancer Res. 2007 Apr 15;67(8):3871-7. doi: 10.1158/0008-5472.CAN-07-0493. Epub 2007 Apr 5. Cancer Res. 2007. PMID: 17413002

10

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure.

Kimura H, Ng JM, Curran T. Kimura H, et al. Among authors: curran t. Cancer Cell. 2008 Mar;13(3):249-60. doi: 10.1016/j.ccr.2008.01.027. Cancer Cell. 2008. PMID: 18328428 Free article.

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