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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK, Teslovich TM, Blackwell TW, Bork-Jensen J, Burtt NP, Chen Y, Green T, Hartl C, Kang HM, Kumar A, Ladenvall C, Ma C, Moutsianas L, Pearson RD, Perry JRB, Rayner NW, Robertson NR, Scott LJ, van de Bunt M, Eriksson JG, Jula A, Koskinen S, Lehtimäki T, Palotie A, Raitakari OT, Jacobs SBR, Wessel J, Chu AY, Scott RA, Goodarzi MO, Blancher C, Buck G, Buck D, Chines PS, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Trakalo J, Banks E, Carey J, Carneiro MO, DePristo M, Farjoun Y, Fennell T, Goldstein JI, Grant G, Hrabé de Angelis M, Maguire J, Neale BM, Poplin R, Purcell S, Schwarzmayr T, Shakir K, Smith JD, Strom TM, Wieland T, Lindstrom J, Brandslund I, Christensen C, Surdulescu GL, Lakka TA, Doney ASF, Nilsson P, Wareham NJ, Langenberg C, Varga TV, Franks PW, Rolandsson O, Rosengren AH, Farook VS, Thameem F, Puppala S, Kumar S, Lehman DM, Jenkinson CP, Curran … See abstract for full author list ➔ Manning A, et al. Among authors: curran je. Diabetes. 2017 Jul;66(7):2019-2032. doi: 10.2337/db16-1329. Epub 2017 Mar 24. Diabetes. 2017. PMID: 28341696 Free PMC article.
Genetic variation at the FTO locus influences RBL2 gene expression.
Jowett JB, Curran JE, Johnson MP, Carless MA, Göring HH, Dyer TD, Cole SA, Comuzzie AG, MacCluer JW, Moses EK, Blangero J. Jowett JB, et al. Among authors: curran je. Diabetes. 2010 Mar;59(3):726-32. doi: 10.2337/db09-1277. Epub 2009 Dec 15. Diabetes. 2010. PMID: 20009087 Free PMC article.
The characterization of Abelson helper integration site-1 in skeletal muscle and its links to the metabolic syndrome.
Prior MJ, Foletta VC, Jowett JB, Segal DH, Carless MA, Curran JE, Dyer TD, Moses EK, McAinch AJ, Konstantopoulos N, Bozaoglu K, Collier GR, Cameron-Smith D, Blangero J, Walder KR. Prior MJ, et al. Among authors: curran je. Metabolism. 2010 Jul;59(7):1057-64. doi: 10.1016/j.metabol.2009.11.002. Epub 2009 Dec 31. Metabolism. 2010. PMID: 20045148 Free PMC article.
Genetic Analysis Workshop 17 mini-exome simulation.
Almasy L, Dyer TD, Peralta JM, Kent JW Jr, Charlesworth JC, Curran JE, Blangero J. Almasy L, et al. Among authors: curran je. BMC Proc. 2011 Nov 29;5 Suppl 9(Suppl 9):S2. doi: 10.1186/1753-6561-5-S9-S2. BMC Proc. 2011. PMID: 22373155 Free PMC article.
Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans.
Farook VS, Puppala S, Schneider J, Fowler SP, Chittoor G, Dyer TD, Allayee H, Cole SA, Arya R, Black MH, Curran JE, Almasy L, Buchanan TA, Jenkinson CP, Lehman DM, Watanabe RM, Blangero J, Duggirala R. Farook VS, et al. Among authors: curran je. Obesity (Silver Spring). 2012 Oct;20(10):2083-92. doi: 10.1038/oby.2012.74. Epub 2012 Mar 29. Obesity (Silver Spring). 2012. PMID: 22456541 Free PMC article.
Utilizing extended pedigree information for discovery and confirmation of copy number variable regions among Mexican Americans.
Blackburn A, Göring HH, Dean A, Carless MA, Dyer T, Kumar S, Fowler S, Curran JE, Almasy L, Mahaney M, Comuzzie A, Duggirala R, Blangero J, Lehman DM. Blackburn A, et al. Among authors: curran je. Eur J Hum Genet. 2013 Apr;21(4):404-9. doi: 10.1038/ejhg.2012.188. Epub 2012 Aug 22. Eur J Hum Genet. 2013. PMID: 22909773 Free PMC article.
265 results