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Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis.
Hollinshead KER, Munford H, Eales KL, Bardella C, Li C, Escribano-Gonzalez C, Thakker A, Nonnenmacher Y, Kluckova K, Jeeves M, Murren R, Cuozzo F, Ye D, Laurenti G, Zhu W, Hiller K, Hodson DJ, Hua W, Tomlinson IP, Ludwig C, Mao Y, Tennant DA. Hollinshead KER, et al. Among authors: cuozzo f. Cell Rep. 2018 Mar 20;22(12):3107-3114. doi: 10.1016/j.celrep.2018.02.084. Cell Rep. 2018. PMID: 29562167 Free PMC article.
Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion.
Viloria K, Nasteska D, Briant LJB, Heising S, Larner DP, Fine NHF, Ashford FB, da Silva Xavier G, Ramos MJ, Hasib A, Cuozzo F, Manning Fox JE, MacDonald PE, Akerman I, Lavery GG, Flaxman C, Morgan NG, Richardson SJ, Hewison M, Hodson DJ. Viloria K, et al. Among authors: cuozzo f. Cell Rep. 2020 Jun 16;31(11):107761. doi: 10.1016/j.celrep.2020.107761. Cell Rep. 2020. PMID: 32553153 Free PMC article.
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release.
Nasteska D, Fine NHF, Ashford FB, Cuozzo F, Viloria K, Smith G, Dahir A, Dawson PWJ, Lai YC, Bastidas-Ponce A, Bakhti M, Rutter GA, Fiancette R, Nano R, Piemonti L, Lickert H, Zhou Q, Akerman I, Hodson DJ. Nasteska D, et al. Among authors: cuozzo f. Nat Commun. 2021 Jan 29;12(1):674. doi: 10.1038/s41467-020-20632-z. Nat Commun. 2021. PMID: 33514698 Free PMC article.
Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice.
Nasteska D, Cuozzo F, Viloria K, Johnson EM, Thakker A, Bany Bakar R, Westbrook RL, Barlow JP, Hoang M, Joseph JW, Lavery GG, Akerman I, Cantley J, Hodson L, Tennant DA, Hodson DJ. Nasteska D, et al. Among authors: cuozzo f. JCI Insight. 2021 Aug 23;6(16):e140288. doi: 10.1172/jci.insight.140288. JCI Insight. 2021. PMID: 34264866 Free PMC article.
Author Correction: PDX1LOW MAFALOW β-cells contribute to islet function and insulin release.
Nasteska D, Fine NHF, Ashford FB, Cuozzo F, Viloria K, Smith G, Dahir A, Dawson PWJ, Lai YC, Bastidas-Ponce A, Bakhti M, Rutter GA, Fiancette R, Nano R, Piemonti L, Lickert H, Zhou Q, Akerman I, Hodson DJ. Nasteska D, et al. Among authors: cuozzo f. Nat Commun. 2021 Jul 20;12(1):4521. doi: 10.1038/s41467-021-24848-5. Nat Commun. 2021. PMID: 34285239 Free PMC article. No abstract available.
Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions.
Westbrook RL, Bridges E, Roberts J, Escribano-Gonzalez C, Eales KL, Vettore LA, Walker PD, Vera-Siguenza E, Rana H, Cuozzo F, Eskla KL, Vellama H, Shaaban A, Nixon C, Luuk H, Lavery GG, Hodson DJ, Harris AL, Tennant DA. Westbrook RL, et al. Among authors: cuozzo f. Cell Rep. 2022 Feb 1;38(5):110320. doi: 10.1016/j.celrep.2022.110320. Cell Rep. 2022. PMID: 35108535 Free PMC article.
80 results