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Page 1
IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels.
Faiz A, Mahbub RM, Boedijono FS, Tomassen MI, Kooistra W, Timens W, Nawijn M, Hansbro PM, Johansen MD, Pouwels SD, Heijink IH, Massip F, de Biase MS, Schwarz RF, Adcock IM, Chung KF, van der Does A, Hiemstra PS, Goulaouic H, Xing H, Abdulai R, de Rinaldis E, Cunoosamy D, Harel S, Lederer D, Nivens MC, Wark PA, Kerstjens HAM, Hylkema MN, Brandsma CA, van den Berge M. Faiz A, et al. Among authors: cunoosamy d. Am J Respir Crit Care Med. 2023 Nov 15;208(10):1075-1087. doi: 10.1164/rccm.202210-1881OC. Am J Respir Crit Care Med. 2023. PMID: 37708400 Free PMC article.
Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study.
Kolmert J, Gómez C, Balgoma D, Sjödin M, Bood J, Konradsen JR, Ericsson M, Thörngren JO, James A, Mikus M, Sousa AR, Riley JH, Bates S, Bakke PS, Pandis I, Caruso M, Chanez P, Fowler SJ, Geiser T, Howarth P, Horváth I, Krug N, Montuschi P, Sanak M, Behndig A, Shaw DE, Knowles RG, Holweg CTJ, Wheelock ÅM, Dahlén B, Nordlund B, Alving K, Hedlin G, Chung KF, Adcock IM, Sterk PJ, Djukanovic R, Dahlén SE, Wheelock CE; U-BIOPRED Study Group, on behalf of the U-BIOPRED Study Group. Kolmert J, et al. Am J Respir Crit Care Med. 2021 Jan 1;203(1):37-53. doi: 10.1164/rccm.201909-1869OC. Am J Respir Crit Care Med. 2021. PMID: 32667261 Free PMC article.
Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation.
Versi A, Ivan FX, Abdel-Aziz MI, Bates S, Riley J, Baribaud F, Kermani NZ, Montuschi P, Dahlen SE, Djukanovic R, Sterk P, Maitland-Van Der Zee AH, Chotirmall SH, Howarth P, Adcock IM, Chung KF; U-BIOPRED consortium. Versi A, et al. Allergy. 2023 Nov;78(11):2906-2920. doi: 10.1111/all.15776. Epub 2023 Jun 7. Allergy. 2023. PMID: 37287344
ARL5b inhibits human rhinovirus 16 propagation and impairs macrophage-mediated bacterial clearance.
Faure-Dupuy S, Jubrail J, Depierre M, Africano-Gomez K, Öberg L, Israelsson E, Thörn K, Delevoye C, Castellano F, Herit F, Guilbert T, Russell DG, Mayer G, Cunoosamy DM, Kurian N, Niedergang F. Faure-Dupuy S, et al. Among authors: cunoosamy dm. EMBO Rep. 2024 Mar;25(3):1156-1175. doi: 10.1038/s44319-024-00069-x. Epub 2024 Feb 8. EMBO Rep. 2024. PMID: 38332148 Free PMC article.
Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA).
Khaleva E, Rattu A, Brightling C, Bush A, Bossios A, Bourdin A, Chung KF, Chaudhuri R, Coleman C, Dahlén SE, Djukanovic R, Deschildre A, Fleming L, Fowler SJ, Gupta A, Hamelmann E, Hashimoto S, Hedlin G, Koppelman GH, Melén E, Murray CS, Pilette C, Porsbjerg C, Pike KC, Rusconi F, Williams C, Ahrens B, Alter P, Anckers F, van den Berge M, Blumchen K, Brusselle G, Clarke GW, Cunoosamy D, Dahlén B, Dixey P, Exley A, Frey U, Gaillard EA, Giovannini-Chami L, Grigg J, Hartenstein D, Heaney LG, Karadag B, Kaul S, Kull I, Licari A, Maitland-van der Zee AH, Mahler V, Schoos AM, Nagakumar P, Negus J, Nielsen H, Paton J, Pijnenburg M, Ramiconi V, Romagosa Vilarnau S, Principe S, Rutjes N, Saglani S, Seddon P, Singer F, Staudinger H, Turner S, Vijverberg S, Winders T, Yasinska V, Roberts G; COMSA Working Group in the 3TR Consortium. Khaleva E, et al. Among authors: cunoosamy d. Eur Respir J. 2023 Apr 3;61(4):2200606. doi: 10.1183/13993003.00606-2022. Print 2023 Apr. Eur Respir J. 2023. PMID: 36229046 Free PMC article. Review.
Dupilumab efficacy and biomarkers in chronic rhinosinusitis with nasal polyps: Association between dupilumab treatment effect on nasal polyp score and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUS-24 and SINUS-52 trials.
Bachert C, Corren J, Lee SE, Zhang H, Harel S, Cunoosamy D, Khan AH, Jacob-Nara JA, Siddiqui S, Nash S, Rowe PJ, Deniz Y. Bachert C, et al. Among authors: cunoosamy d. Int Forum Allergy Rhinol. 2022 Sep;12(9):1191-1195. doi: 10.1002/alr.22964. Epub 2022 Jan 31. Int Forum Allergy Rhinol. 2022. PMID: 34970860 Free PMC article. No abstract available.
Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease.
Naessens T, Morias Y, Hamrud E, Gehrmann U, Budida R, Mattsson J, Baker T, Skogberg G, Israelsson E, Thörn K, Schuijs MJ, Angermann B, Melville F, Staples KJ, Cunoosamy DM, Lambrecht BN. Naessens T, et al. Among authors: cunoosamy dm. Am J Respir Crit Care Med. 2020 Aug 15;202(4):535-548. doi: 10.1164/rccm.201906-1123OC. Am J Respir Crit Care Med. 2020. PMID: 32255375
Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD.
Kurian N, Cohen TS, Öberg L, De Zan E, Skogberg G, Vollmer S, Baturcam E, Svanberg P, Bonn B, Smith PD, Vaarala O, Cunoosamy DM. Kurian N, et al. Among authors: cunoosamy dm. Int J Chron Obstruct Pulmon Dis. 2019 Nov 26;14:2611-2624. doi: 10.2147/COPD.S211619. eCollection 2019. Int J Chron Obstruct Pulmon Dis. 2019. PMID: 32063702 Free PMC article.
Design, Synthesis, and Biological Evaluation of MEK PROTACs.
Vollmer S, Cunoosamy D, Lv H, Feng H, Li X, Nan Z, Yang W, Perry MWD. Vollmer S, et al. Among authors: cunoosamy d. J Med Chem. 2020 Jan 9;63(1):157-162. doi: 10.1021/acs.jmedchem.9b00810. Epub 2019 Dec 20. J Med Chem. 2020. PMID: 31804822
Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus.
Jubrail J, Africano-Gomez K, Herit F, Mularski A, Bourdoncle P, Oberg L, Israelsson E, Burgel PR, Mayer G, Cunoosamy DM, Kurian N, Niedergang F. Jubrail J, et al. Among authors: cunoosamy dm. EMBO Rep. 2020 Jan 7;21(1):e47963. doi: 10.15252/embr.201947963. Epub 2019 Nov 13. EMBO Rep. 2020. PMID: 31721415 Free PMC article.
23 results