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RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase N, Foster DJ, Cunningham MW, Bercher J, Nguyen T, Shulga-Morskaya S, Milstein S, Shaikh S, Rollins J, Golic M, Herse F, Kräker K, Bendix I, Serdar M, Napieczynska H, Heuser A, Gellhaus A, Thiele K, Wallukat G, Müller DN, LaMarca B, Dechend R. Haase N, et al. Among authors: cunningham mw. J Clin Invest. 2020 Jun 1;130(6):2928-2942. doi: 10.1172/JCI99417. J Clin Invest. 2020. PMID: 32338644 Free PMC article. No abstract available.
Preeclampsia: long-term consequences for vascular health.
Amaral LM, Cunningham MW Jr, Cornelius DC, LaMarca B. Amaral LM, et al. Among authors: cunningham mw jr. Vasc Health Risk Manag. 2015 Jul 15;11:403-15. doi: 10.2147/VHRM.S64798. eCollection 2015. Vasc Health Risk Manag. 2015. PMID: 26203257 Free PMC article. Review.
Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4+ T lymphocytes from RUPP rats.
Cornelius DC, Castillo J, Porter J, Amaral LM, Campbell N, Paige A, Thomas AJ, Harmon A, Cunningham MW Jr, Wallace K, Herse F, Wallukat G, Dechend R, LaMarca B. Cornelius DC, et al. Among authors: cunningham mw jr. Am J Physiol Regul Integr Comp Physiol. 2015 Nov 15;309(10):R1243-50. doi: 10.1152/ajpregu.00273.2015. Epub 2015 Aug 26. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 26310940 Free PMC article.
Vitamin D supplementation improves pathophysiology in a rat model of preeclampsia.
Faulkner JL, Cornelius DC, Amaral LM, Harmon AC, Cunningham MW Jr, Darby MM, Ibrahim T, Thomas DS, Herse F, Wallukat G, Dechend R, LaMarca B. Faulkner JL, et al. Among authors: cunningham mw jr. Am J Physiol Regul Integr Comp Physiol. 2016 Feb 15;310(4):R346-54. doi: 10.1152/ajpregu.00388.2015. Epub 2015 Dec 16. Am J Physiol Regul Integr Comp Physiol. 2016. PMID: 26676250 Free PMC article.
The role of inflammation in the pathology of preeclampsia.
Harmon AC, Cornelius DC, Amaral LM, Faulkner JL, Cunningham MW Jr, Wallace K, LaMarca B. Harmon AC, et al. Among authors: cunningham mw jr. Clin Sci (Lond). 2016 Mar;130(6):409-19. doi: 10.1042/CS20150702. Clin Sci (Lond). 2016. PMID: 26846579 Free PMC article. Review.
Identifying immune mechanisms mediating the hypertension during preeclampsia.
LaMarca B, Cornelius DC, Harmon AC, Amaral LM, Cunningham MW, Faulkner JL, Wallace K. LaMarca B, et al. Among authors: cunningham mw. Am J Physiol Regul Integr Comp Physiol. 2016 Jul 1;311(1):R1-9. doi: 10.1152/ajpregu.00052.2016. Epub 2016 Apr 20. Am J Physiol Regul Integr Comp Physiol. 2016. PMID: 27097659 Free PMC article. Review.
Serelaxin improves the pathophysiology of placental ischemia in the reduced uterine perfusion pressure rat model of preeclampsia.
Santiago-Font JA, Amaral LM, Faulkner J, Ibrahim T, Vaka VR, Cunningham MW, LaMarca B. Santiago-Font JA, et al. Among authors: cunningham mw. Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1158-R1163. doi: 10.1152/ajpregu.00192.2016. Epub 2016 Sep 14. Am J Physiol Regul Integr Comp Physiol. 2016. PMID: 27629886 Free PMC article.
Vitamin D supplementation reduces some AT1-AA-induced downstream targets implicated in preeclampsia including hypertension.
Faulkner JL, Amaral LM, Cornelius DC, Cunningham MW, Ibrahim T, Heep A, Campbell N, Usry N, Wallace K, Herse F, Dechend R, LaMarca B. Faulkner JL, et al. Among authors: cunningham mw. Am J Physiol Regul Integr Comp Physiol. 2017 Jan 1;312(1):R125-R131. doi: 10.1152/ajpregu.00218.2016. Epub 2016 Nov 30. Am J Physiol Regul Integr Comp Physiol. 2017. PMID: 27903510 Free PMC article.
227 results