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Formulation, inflammation, and RNA sensing impact the immunogenicity of self-amplifying RNA vaccines.
Mol Ther Nucleic Acids. 2022 Dec 5;31:29-42. doi: 10.1016/j.omtn.2022.11.024. eCollection 2023 Mar 14.
Mol Ther Nucleic Acids. 2022.
PMID: 36589712
Free PMC article.
Synthesis of protein conjugates adsorbed on cationic liposomes surface.
Chatzikleanthous D, Cunliffe R, Carboni F, Romano MR, O'Hagan DT, Roberts CW, Perrie Y, Adamo R.
Chatzikleanthous D, et al.
MethodsX. 2020 May 28;7:100942. doi: 10.1016/j.mex.2020.100942. eCollection 2020.
MethodsX. 2020.
PMID: 32551244
Free PMC article.
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Reducing cell intrinsic immunity to mRNA vaccine alters adaptive immune responses in mice.
Wang Z, Jacobus EJ, Stirling DC, Krumm S, Flight KE, Cunliffe RF, Mottl J, Singh C, Mosscrop LG, Santiago LA, Vogel AB, Kariko K, Sahin U, Erbar S, Tregoning JS.
Wang Z, et al. Among authors: cunliffe rf.
Mol Ther Nucleic Acids. 2023 Oct 5;34:102045. doi: 10.1016/j.omtn.2023.102045. eCollection 2023 Dec 12.
Mol Ther Nucleic Acids. 2023.
PMID: 37876532
Free PMC article.
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Optimizing a linear 'Doggybone' DNA vaccine for influenza virus through the incorporation of DNA targeting sequences and neuraminidase antigen.
Cunliffe RF, Stirling DC, Razzano I, Murugaiah V, Montomoli E, Kim S, Wane M, Horton H, Caproni LJ, Tregoning JS.
Cunliffe RF, et al.
Discov Immunol. 2024 Jan 3;3(1):kyad030. doi: 10.1093/discim/kyad030. eCollection 2024.
Discov Immunol. 2024.
PMID: 38567290
Free PMC article.
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Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses.
Anderluzzi G, Schmidt ST, Cunliffe R, Woods S, Roberts CW, Veggi D, Ferlenghi I, O'Hagan DT, Baudner BC, Perrie Y.
Anderluzzi G, et al.
J Control Release. 2021 Feb 10;330:933-944. doi: 10.1016/j.jconrel.2020.10.066. Epub 2020 Nov 2.
J Control Release. 2021.
PMID: 33152394
Free article.
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Design of a novel vaccine nanotechnology-based delivery system comprising CpGODN-protein conjugate anchored to liposomes.
Chatzikleanthous D, Schmidt ST, Buffi G, Paciello I, Cunliffe R, Carboni F, Romano MR, O'Hagan DT, D'Oro U, Woods S, Roberts CW, Perrie Y, Adamo R.
Chatzikleanthous D, et al.
J Control Release. 2020 Jul 10;323:125-137. doi: 10.1016/j.jconrel.2020.04.001. Epub 2020 Apr 2.
J Control Release. 2020.
PMID: 32247804
Free article.
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