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Formulation, inflammation, and RNA sensing impact the immunogenicity of self-amplifying RNA vaccines.
Tregoning JS, Stirling DC, Wang Z, Flight KE, Brown JC, Blakney AK, McKay PF, Cunliffe RF, Murugaiah V, Fox CB, Beattie M, Tam YK, Johansson C, Shattock RJ. Tregoning JS, et al. Among authors: cunliffe rf. Mol Ther Nucleic Acids. 2022 Dec 5;31:29-42. doi: 10.1016/j.omtn.2022.11.024. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2022. PMID: 36589712 Free PMC article.
Synthesis of protein conjugates adsorbed on cationic liposomes surface.
Chatzikleanthous D, Cunliffe R, Carboni F, Romano MR, O'Hagan DT, Roberts CW, Perrie Y, Adamo R. Chatzikleanthous D, et al. MethodsX. 2020 May 28;7:100942. doi: 10.1016/j.mex.2020.100942. eCollection 2020. MethodsX. 2020. PMID: 32551244 Free PMC article.
Reducing cell intrinsic immunity to mRNA vaccine alters adaptive immune responses in mice.
Wang Z, Jacobus EJ, Stirling DC, Krumm S, Flight KE, Cunliffe RF, Mottl J, Singh C, Mosscrop LG, Santiago LA, Vogel AB, Kariko K, Sahin U, Erbar S, Tregoning JS. Wang Z, et al. Among authors: cunliffe rf. Mol Ther Nucleic Acids. 2023 Oct 5;34:102045. doi: 10.1016/j.omtn.2023.102045. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 37876532 Free PMC article.