Cunha RA - Search Results

1

Lateral septum adenosine A_2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula.

Wang M, Li P, Li Z, da Silva BS, Zheng W, Xiang Z, He Y, Xu T, Cordeiro C, Deng L, Dai Y, Ye M, Lin Z, Zhou J, Zhou X, Ye F, Cunha RA, Chen J, Guo W. Wang M, et al. Among authors: cunha ra. Nat Commun. 2023 Apr 5;14(1):1880. doi: 10.1038/s41467-023-37601-x. Nat Commun. 2023. PMID: 37019936 Free PMC article.

2

A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs.

Shen HY, Coelho JE, Ohtsuka N, Canas PM, Day YJ, Huang QY, Rebola N, Yu L, Boison D, Cunha RA, Linden J, Tsien JZ, Chen JF. Shen HY, et al. Among authors: cunha ra. J Neurosci. 2008 Mar 19;28(12):2970-5. doi: 10.1523/JNEUROSCI.5255-07.2008. J Neurosci. 2008. PMID: 18354001 Free PMC article.

3

Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders.

Cunha RA, Ferré S, Vaugeois JM, Chen JF. Cunha RA, et al. Curr Pharm Des. 2008;14(15):1512-24. doi: 10.2174/138161208784480090. Curr Pharm Des. 2008. PMID: 18537674 Free PMC article. Review.

4

Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes.

Matos M, Augusto E, Santos-Rodrigues AD, Schwarzschild MA, Chen JF, Cunha RA, Agostinho P. Matos M, et al. Among authors: cunha ra. Glia. 2012 May;60(5):702-16. doi: 10.1002/glia.22290. Epub 2012 Feb 1. Glia. 2012. PMID: 22298379

5

Regulation of fear responses by striatal and extrastriatal adenosine A2A receptors in forebrain.

Wei CJ, Augusto E, Gomes CA, Singer P, Wang Y, Boison D, Cunha RA, Yee BK, Chen JF. Wei CJ, et al. Among authors: cunha ra. Biol Psychiatry. 2014 Jun 1;75(11):855-63. doi: 10.1016/j.biopsych.2013.05.003. Epub 2013 Jun 29. Biol Psychiatry. 2014. PMID: 23820821 Free PMC article.

6

Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions.

Augusto E, Matos M, Sévigny J, El-Tayeb A, Bynoe MS, Müller CE, Cunha RA, Chen JF. Augusto E, et al. Among authors: cunha ra. J Neurosci. 2013 Jul 10;33(28):11390-9. doi: 10.1523/JNEUROSCI.5817-12.2013. J Neurosci. 2013. PMID: 23843511 Free PMC article.

7

Antagonistic interaction between adenosine A2A receptors and Na+/K+-ATPase-α2 controlling glutamate uptake in astrocytes.

Matos M, Augusto E, Agostinho P, Cunha RA, Chen JF. Matos M, et al. Among authors: cunha ra. J Neurosci. 2013 Nov 20;33(47):18492-502. doi: 10.1523/JNEUROSCI.1828-13.2013. J Neurosci. 2013. PMID: 24259572 Free PMC article.

8

Adenosine A₂A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation.

Shen HY, Canas PM, Garcia-Sanz P, Lan JQ, Boison D, Moratalla R, Cunha RA, Chen JF. Shen HY, et al. Among authors: cunha ra. PLoS One. 2013 Nov 28;8(11):e80902. doi: 10.1371/journal.pone.0080902. eCollection 2013. PLoS One. 2013. PMID: 24312250 Free PMC article.

9

Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory.

Li P, Rial D, Canas PM, Yoo JH, Li W, Zhou X, Wang Y, van Westen GJ, Payen MP, Augusto E, Gonçalves N, Tomé AR, Li Z, Wu Z, Hou X, Zhou Y, IJzerman AP, Boyden ES, Cunha RA, Qu J, Chen JF. Li P, et al. Among authors: cunha ra. Mol Psychiatry. 2015 Nov;20(11):1339-49. doi: 10.1038/mp.2014.182. Epub 2015 Feb 17. Mol Psychiatry. 2015. PMID: 25687775 Free PMC article.

10

Deletion of adenosine A2A receptors from astrocytes disrupts glutamate homeostasis leading to psychomotor and cognitive impairment: relevance to schizophrenia.

Matos M, Shen HY, Augusto E, Wang Y, Wei CJ, Wang YT, Agostinho P, Boison D, Cunha RA, Chen JF. Matos M, et al. Among authors: cunha ra. Biol Psychiatry. 2015 Dec 1;78(11):763-74. doi: 10.1016/j.biopsych.2015.02.026. Epub 2015 Feb 27. Biol Psychiatry. 2015. PMID: 25869810 Free PMC article.

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