Cunha MR - Search Results

1

Peppers: A "Hot" Natural Source for Antitumor Compounds.

Cunha MR, Tavares MT, Fernandes TB, Parise-Filho R. Cunha MR, et al. Molecules. 2021 Mar 10;26(6):1521. doi: 10.3390/molecules26061521. Molecules. 2021. PMID: 33802144 Free PMC article. Review.

2

Oleanolic acid (OA) as an antileishmanial agent: Biological evaluation and in silico mechanistic insights.

Melo TS, Gattass CR, Soares DC, Cunha MR, Ferreira C, Tavares MT, Saraiva E, Parise-Filho R, Braden H, Delorenzi JC. Melo TS, et al. Among authors: cunha mr. Parasitol Int. 2016 Jun;65(3):227-37. doi: 10.1016/j.parint.2016.01.001. Epub 2016 Jan 6. Parasitol Int. 2016. PMID: 26772973

3

Synthesis, Molecular Modeling, and Evaluation of Novel Sulfonylhydrazones as Acetylcholinesterase Inhibitors for Alzheimer's Disease.

Fernandes TB, Cunha MR, Sakata RP, Candido TM, Baby AR, Tavares MT, Barbosa EG, Almeida WP, Parise-Filho R. Fernandes TB, et al. Among authors: cunha mr. Arch Pharm (Weinheim). 2017 Nov;350(11). doi: 10.1002/ardp.201700163. Epub 2017 Sep 22. Arch Pharm (Weinheim). 2017. PMID: 28940630

4

Multi-Spectroscopic and Theoretical Analysis on the Interaction between Human Serum Albumin and a Capsaicin Derivative-RPF101.

Chaves OA, Tavares MT, Cunha MR, Parise-Filho R, Sant'Anna CMR, Netto-Ferreira JC. Chaves OA, et al. Among authors: cunha mr. Biomolecules. 2018 Aug 23;8(3):78. doi: 10.3390/biom8030078. Biomolecules. 2018. PMID: 30142945 Free PMC article.

5

Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling.

Pereira GJV, Tavares MT, Azevedo RA, Martins BB, Cunha MR, Bhardwaj R, Cury Y, Zambelli VO, Barbosa EG, Hediger MA, Parise-Filho R. Pereira GJV, et al. Among authors: cunha mr. Bioorg Med Chem. 2019 Jul 1;27(13):2893-2904. doi: 10.1016/j.bmc.2019.05.020. Epub 2019 May 14. Bioorg Med Chem. 2019. PMID: 31104785

6

Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor.

Cunha MR, Bhardwaj R, Carrel AL, Lindinger S, Romanin C, Parise-Filho R, Hediger MA, Reymond JL. Cunha MR, et al. RSC Med Chem. 2020 Jul 16;11(9):1032-1040. doi: 10.1039/d0md00145g. eCollection 2020 Sep 1. RSC Med Chem. 2020. PMID: 33479695 Free PMC article.

7

Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors.

Takarada JE, Cunha MR, Almeida VM, Vasconcelos SNS, Santiago AS, Godoi PH, Salmazo A, Ramos PZ, Fala AM, de Souza LR, Da Silva IEP, Bengtson MH, Massirer KB, Couñago RM. Takarada JE, et al. Among authors: cunha mr. Bioorg Med Chem. 2024 Jan 15;98:117561. doi: 10.1016/j.bmc.2023.117561. Epub 2023 Dec 20. Bioorg Med Chem. 2024. PMID: 38157838 Free article.

8

A novel BRET-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells.

Cunha MR, Catta-Preta CMC, Takarada JE, Moreira GA, Massirer KB, Couñago RM. Cunha MR, et al. J Biol Chem. 2023 Jun;299(6):104807. doi: 10.1016/j.jbc.2023.104807. Epub 2023 May 11. J Biol Chem. 2023. PMID: 37172730 Free PMC article.

9

Discovery of novel benzothiophene derivatives as potent and narrow spectrum inhibitors of DYRK1A and DYRK1B.

Segretti ND, Takarada JE, Ferreira MA Jr, da Silva Santiago A, Teodoro BVM, Damião MCFCB, Godoi PH, Cunha MR, Fala AM, Ramos PZ, Ishikawa EE, Mascarello A, Serafim RAM, Azevedo H, Guimarães CRW, Couñago RM. Segretti ND, et al. Among authors: cunha mr. Bioorg Med Chem Lett. 2022 Jul 15;68:128764. doi: 10.1016/j.bmcl.2022.128764. Epub 2022 May 2. Bioorg Med Chem Lett. 2022. PMID: 35504513

10

Use of Plant Extracts in Polymeric Scaffolds in the Regeneration of Mandibular Injuries.

de Oliveira BEG, Maia FLM, Massimino LC, Garcia CF, Plepis AMG, Martins VDCA, Reis CHB, Silva VR, Bezerra AA, Pauris CC, Buchaim DV, Silva YBE, Buchaim RL, da Cunha MR. de Oliveira BEG, et al. Among authors: da cunha mr. Pharmaceutics. 2024 Apr 2;16(4):491. doi: 10.3390/pharmaceutics16040491. Pharmaceutics. 2024. PMID: 38675152 Free PMC article.

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