Cullen S - Search Results

1

Galactosialidosis: preclinical enzyme replacement therapy in a mouse model of the disease, a proof of concept.

Cadaoas J, Hu H, Boyle G, Gomero E, Mosca R, Jayashankar K, Machado M, Cullen S, Guzman B, van de Vlekkert D, Annunziata I, Vellard M, Kakkis E, Koppaka V, d'Azzo A. Cadaoas J, et al. Among authors: cullen s. Mol Ther Methods Clin Dev. 2020 Nov 20;20:191-203. doi: 10.1016/j.omtm.2020.11.012. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2020. PMID: 33426146 Free PMC article.

2

Vestronidase alfa: Recombinant human β-glucuronidase as an enzyme replacement therapy for MPS VII.

Cadaoas J, Boyle G, Jungles S, Cullen S, Vellard M, Grubb JH, Jurecka A, Sly W, Kakkis E. Cadaoas J, et al. Among authors: cullen s. Mol Genet Metab. 2020 May;130(1):65-76. doi: 10.1016/j.ymgme.2020.02.009. Epub 2020 Mar 6. Mol Genet Metab. 2020. PMID: 32192868 Free article. Clinical Trial.

3

RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity.

Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, Chen-Harris H, Cullen SP, Snyder AG, Ralli-Jain P, Frase S, Tait SWG, Green DR, Albert ML, Oberst A. Orozco SL, et al. Among authors: cullen sp. Cell Rep. 2019 Aug 27;28(9):2275-2287.e5. doi: 10.1016/j.celrep.2019.07.077. Cell Rep. 2019. PMID: 31461645 Free PMC article.

4

Bcl-2 family proteins participate in mitochondrial quality control by regulating Parkin/PINK1-dependent mitophagy.

Hollville E, Carroll RG, Cullen SP, Martin SJ. Hollville E, et al. Mol Cell. 2014 Aug 7;55(3):451-66. doi: 10.1016/j.molcel.2014.06.001. Epub 2014 Jul 3. Mol Cell. 2014. PMID: 24999239 Free article.

5

TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation.

Sullivan GP, O'Connor H, Henry CM, Davidovich P, Clancy DM, Albert ML, Cullen SP, Martin SJ. Sullivan GP, et al. Dev Cell. 2020 Mar 23;52(6):714-730.e5. doi: 10.1016/j.devcel.2020.01.031. Epub 2020 Feb 27. Dev Cell. 2020. PMID: 32109381 Free article.

6

Fas/CD95-induced chemokines can serve as "find-me" signals for apoptotic cells.

Cullen SP, Henry CM, Kearney CJ, Logue SE, Feoktistova M, Tynan GA, Lavelle EC, Leverkus M, Martin SJ. Cullen SP, et al. Mol Cell. 2013 Mar 28;49(6):1034-48. doi: 10.1016/j.molcel.2013.01.025. Epub 2013 Feb 21. Mol Cell. 2013. PMID: 23434371 Free article.

7

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.

Kearney CJ, Cullen SP, Tynan GA, Henry CM, Clancy D, Lavelle EC, Martin SJ. Kearney CJ, et al. Among authors: cullen sp. Cell Death Differ. 2015 Aug;22(8):1313-27. doi: 10.1038/cdd.2014.222. Epub 2015 Jan 23. Cell Death Differ. 2015. PMID: 25613374 Free PMC article.

8

RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.

Kearney CJ, Cullen SP, Clancy D, Martin SJ. Kearney CJ, et al. FEBS J. 2014 Nov;281(21):4921-34. doi: 10.1111/febs.13034. Epub 2014 Oct 4. FEBS J. 2014. PMID: 25195660 Free article.

9

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis.

Cullen SP, Kearney CJ, Clancy DM, Martin SJ. Cullen SP, et al. Cell Rep. 2015 Jun 16;11(10):1535-48. doi: 10.1016/j.celrep.2015.05.003. Epub 2015 May 28. Cell Rep. 2015. PMID: 26027935 Free article.

10

Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production.

Kearney CJ, Sheridan C, Cullen SP, Tynan GA, Logue SE, Afonina IS, Vucic D, Lavelle EC, Martin SJ. Kearney CJ, et al. Among authors: cullen sp. J Biol Chem. 2013 Feb 15;288(7):4878-90. doi: 10.1074/jbc.M112.422410. Epub 2012 Dec 28. J Biol Chem. 2013. PMID: 23275336 Free PMC article.

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