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De novo discovery of serotonin N-acetyltransferase inhibitors.
Szewczuk LM, Saldanha SA, Ganguly S, Bowers EM, Javoroncov M, Karanam B, Culhane JC, Holbert MA, Klein DC, Abagyan R, Cole PA. Szewczuk LM, et al. Among authors: culhane jc. J Med Chem. 2007 Nov 1;50(22):5330-8. doi: 10.1021/jm0706463. Epub 2007 Oct 9. J Med Chem. 2007. PMID: 17924613 Free PMC article.
LSD1 and the chemistry of histone demethylation.
Culhane JC, Cole PA. Culhane JC, et al. Curr Opin Chem Biol. 2007 Oct;11(5):561-8. doi: 10.1016/j.cbpa.2007.07.014. Epub 2007 Sep 11. Curr Opin Chem Biol. 2007. PMID: 17851108 Free PMC article. Review.
Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis.
Tarrant MK, Rho HS, Xie Z, Jiang YL, Gross C, Culhane JC, Yan G, Qian J, Ichikawa Y, Matsuoka T, Zachara N, Etzkorn FA, Hart GW, Jeong JS, Blackshaw S, Zhu H, Cole PA. Tarrant MK, et al. Among authors: culhane jc. Nat Chem Biol. 2012 Jan 22;8(3):262-9. doi: 10.1038/nchembio.771. Nat Chem Biol. 2012. PMID: 22267120 Free PMC article.
Synthesis of novel oxazolidinone antimicrobial agents.
Ebner DC, Culhane JC, Winkelman TN, Haustein MD, Ditty JL, Ippoliti JT. Ebner DC, et al. Among authors: culhane jc. Bioorg Med Chem. 2008 Mar 1;16(5):2651-6. doi: 10.1016/j.bmc.2007.11.040. Epub 2007 Nov 19. Bioorg Med Chem. 2008. PMID: 18077175
14 results